Results 151 to 160 of about 99,491 (262)

ADA2 genotype and enzyme activity may predict vasculitic or hematologic DADA2 phenotype. [PDF]

J Hum Immun
Peters P, Schepp J, Albert MH, von Bernuth H, Blank N, Brunner J, Dückers G, Ehlers L, Farmand S, Föll D, Förster-Waldl E, Gburek-Augustat J, Ghosh S, Göschl L, Hömberg M, Hönig M, Kallinich T, Klemann C, Klingel L, Kontny U, Kuhn LM, Lamprecht P, Lehmberg K, Meyer-Bahlburg A, Müller I, Nathrath M, Niehues T, Oommen PT, Pachlopnik Schmid J, Prader S, Puzik A, Renella R, Schulz A, Skrabl-Baumgartner A, Starke S, Tarrant TK, Hershfield M, Grimbacher B, Hauck F.   +38 more
europepmc   +1 more source

IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α

Animal Models and Experimental Medicine, EarlyView.
IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α. Abstract Background The purpose is to define the contribution of the interferon regulatory factor‐1–dual‐specificity tyrosine phosphorylation‐regulated kinase 1α (IRF‐1–DYRK1α) axis to hepatocellular ferroptosis during liver ischemia/reperfusion injury ...
Jinping Zhang, Jinming Zhang, Siyuan Song, Mingyang Li, Liying Sun, Zhijun Zhu, Dongdong Lin   +6 more
wiley   +1 more source

Building pragmatic transplant immunobiology in Sri Lanka: a concise review with an LMIC lens. [PDF]

Front Transplant
Hewageegana AP.
europepmc   +1 more source

Cell therapy comparison of dental pulp stem cells, hepatocytes, and their exosomes for liver fibrosis treatment in rats

Animal Models and Experimental Medicine, EarlyView.
DPSCs, hepatocytes, and exosomes were tested for liver fibrosis therapy. Exosome‐based treatment exhibited superior antioxidative and regenerative effects. Liver enzymes, oxidative stress, and profibrotic markers were significantly reduced. α‐SMA, desmin, and related gene expression were downregulated.
Sahar Rahimi, Seyedeh Mahdieh Khoshnazar, Ali Derakhshani, Nader Shahrokhi   +3 more
wiley   +1 more source

The Impact of Normothermic Machine Liver Perfusion on Early Renal Outcomes After Simultaneous Liver-kidney Transplantation: A Propensity Score-Matched Analysis. [PDF]

Transplant Direct
Nadeem MA, Wehrle CJ, Satish S, Siddiqui HU, Verma S, Sanha V, Ali K, Khalil M, Pita A, Esfeh JM, Kwon DCH, Aucejo F, Kim J, Pinna AD, Eltemamy M, Miller C, Fujiki M, Fairchild RL, Fatica RA, Hashimoto K, Wee A, Schlegel A, Cleveland Clinic Liver Perfusion Group.   +22 more
europepmc   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

What is the best path towards allogeneic transplantation in MDS and AML? A survey among German-spreaking centers for allogeneic hematopoietic stem cell transplantation. [PDF]

Ann Hematol
Krause SW, Bethge W, Bug G, Elmaagacli A, Jost E, Klein SA, Kobbe G, Kraus S, Krüger WH, Luft T, Müller LP, Schäfer-Eckart K, Schetelig J, Steiner N, Stelljes M, Tischer J, Winkler J, Wolff D, Wortmann F, Röllig C.   +19 more
europepmc   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Engraftment of sheep splenic lymphocytes into NBSGW mice and application in Brucella infection

Animal Models and Experimental Medicine, EarlyView.
A sheep splenocyte‐reconstituted mouse model (Sh‐Spl mice) was established via intravenous injection of sheep splenic lymphocytes into immunodeficient mice to evaluate Brucella infection. Abstract Background The development of immune reconstituted xenograft mouse models has addressed the limitations imposed by interspecies immunological differences in ...
Xiaowei Wang, Shicheng Wan, Yanmin Guo, Hongyu Han, Fei Luo, Dongmei Jiang, Xiaorong Yang, Quanhai Pang, Haisheng Yu, Jinlian Hua   +9 more
wiley   +1 more source

Living Life to the Fullest After Organ Transplantation. [PDF]

Transpl Int
Zajacova A, Annema C, Pilat N, Berney T.
europepmc   +1 more source