Results 191 to 200 of about 99,491 (262)

Comparative Transcriptional Profiling of Key Macrophage and Fibroblast Subpopulations in Rheumatoid Arthritis–Associated Lung Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib   +8 more
wiley   +1 more source

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

open access: yesArthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen   +10 more
wiley   +1 more source

Non‐melanoma skin cancer risk with Janus kinase inhibitors compared to interleukin‐6 receptor inhibitors in rheumatoid arthritis: results from a national cohort study

open access: yesArthritis &Rheumatology, Accepted Article.
Background Non‐melanoma skin cancer (NMSC) is one of the most common malignancies in rheumatoid arthritis (RA). This analysis assessed NMSC risk with Janus kinase inhibitors (JAKi) compared to interleukin‐6 receptor inhibitors (IL‐6Ri). Method This study used data from the British Society for Rheumatology Rheumatoid Arthritis Register (BSRBR‐RA) linked
Zixing Tian   +8 more
wiley   +1 more source

Extracellular Matrix With Bone Marrow Aspirate Concentrate for Osteochondritis Dissecans of the Capitellum in Adolescents

open access: yesArthroscopy Techniques, EarlyView.
Abstract Capitellar osteochondritis dissecans is most frequently encountered in overhead and tumbling adolescent athletes. Traditional management with abrasion chondroplasty or microfracture results in fibrocartilage formation and variable return to sport rates, whereas osteochondral autograft transfer system or osteochondral allograft transplantation ...
Joshua T. Bram   +4 more
wiley   +1 more source

Outcomes following matched sibling donor transplantation for severe combined immunodeficiency: a report from the PIDTC. [PDF]

open access: yesBlood Adv
Rayes A   +52 more
europepmc   +1 more source

Editorial: Anti-HLA DSA and Beyond: Deciphering the Immunological Mechanisms Driving Chronic Rejection. [PDF]

open access: yesTranspl Int
Casiraghi F   +5 more
europepmc   +1 more source

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