Results 11 to 20 of about 8,876 (170)

DESCRIPTIVE ANALYSIS OF HEMATOPOIETIC STEM CELL TRANSPLANTS PERFORMED IN A PUBLIC SERVICE BETWEEN 1984 AND 2023

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introduction: Hematopoietic Stem Cell Transplantation (HSCT) is a treatment modality for some benign and/or malignant diseases that affect blood cells. The first successful HSCT took place in the USA in 1957 and later in Brazil in 1979.
LC Costa-Junior   +5 more
doaj   +1 more source

Health‐related Quality of Life Profile of Newly Diagnosed Patients With Myelodysplastic Syndromes by Age, Sex, and Risk Group: A Real‐world Study by the GIMEMA

open access: yesHemaSphere, Volume 7, Issue 9, September 2023., 2023
Health‐related quality of life (HRQoL) is an important goal of therapy for patients with myelodysplastic syndromes (MDS); however, little is known about HRQoL of these patients at clinical presentation. We report HRQoL profile of newly diagnosed patients with MDS across both the the International Prognostic Scoring System (IPSS) and IPSS‐Revised (IPSS ...
Fabio Efficace   +26 more
wiley   +1 more source

Induced Pluripotent Stem Cells Enable Disease Modeling and Drug Screening in Calreticulin del52 and ins5 Myeloproliferative Neoplasms

open access: yesHemaSphere, Volume 5, Issue 7, July 2021., 2021
Mutations in the calreticulin (CALR) gene are seen in about 30% of essential thrombocythemia and primary myelofibrosis patients. To address the contribution of the human CALR mutants to the pathogenesis of myeloproliferative neoplasms (MPNs) in an endogenous context, we modeled the CALRdel52 and CALRins5 mutants by induced pluripotent stem cell (iPSC ...
Lise Secardin   +13 more
wiley   +1 more source

miRNome Profiling Reveals Shared Features in Breast Cancer Subtypes and Highlights miRNAs That Potentially Regulate MYB and EZH2 Expression

open access: yesFrontiers in Oncology, 2021
Breast cancer (BC) has been extensively studied, as it is one of the more commonly diagnosed cancer types worldwide. The study of miRNAs has increased what is known about the complexity of pathways and signaling and has identified potential biomarkers ...
Stephany Corrêa   +6 more
doaj   +1 more source

Spatial Dispersal of Epstein–Barr Virus in South America Reveals an African American Variant in Brazilian Lymphomas

open access: yesViruses, 2022
Epstein–Barr virus (EBV) is a saliva-borne ɣ-herpesvirus associated with benign and malignant lymphoproliferation. EBV-mediated tumorigenic mechanisms are not fully understood and may be related to viral genetic variations.
Paula Alves   +7 more
doaj   +1 more source

Relato de experiência: abordagem multidisciplinar na anemia aplástica – desenvolvimento de um modelo de assistência ambulatorial

open access: yesHU Revista, 2021
Introdução: A anemia aplástica é uma doença hematológica rara, que cursa com alta morbidade e mortalidade. O tratamento é definido pela idade do paciente, classificação da gravidade, comorbidades existentes e disponibilidade de um doador compatível para ...
Adriana Aparecida Ferreira   +3 more
doaj   +1 more source

Experiência do Centro Nacional de Transplante de Medula Óssea (CEMO) com uso de Cateteres tipo Hickman-Broviac

open access: yesRevista Brasileira de Cancerologia, 2023
 Quarenta e sete pacientes foram admitidos no Centro Nacional de Transplante de Medula Óssea - CEMO - do Rio de Janeiro, tendo sido introduzidos 57 cateteres de Hickman-Broviac.
Eduardo D. Velasco   +2 more
doaj   +1 more source

UM MODELO DE EVOLUÇÃO PARA SÍNDROME MIELODISPLÁSICA PEDIÁTRICA: SOB UM OLHAR CITOGENÉTICO E EPIGENÉTICO

open access: yesHematology, Transfusion and Cell Therapy, 2021
Objetivos: A síndrome mielodisplásica pediátrica (SMD-p) é rara, sua etiopatologia é complexa e ainda não se sabe a causa de seu surgimento. Embora avanços rápidos tenham sido feitos na SMD no adulto, a genética e epigenética da SMD-p ainda são pouco ...
VL Lovatel   +9 more
doaj   +1 more source

Transplante de Medula Óssea

open access: yesRevista Brasileira de Cancerologia, 2023
Artigo de opinião, de Mary Evelyn Dantas Flowers do Instituto Nacional de Câncer (INCA) sobre a função, a finalidade e os resultados obtidos com o transplante de medula óssea (TMO).
Mary Evelyn Dantas Flowers
doaj   +1 more source

Plasma lipoproteins, triglycerides and glucose profile of cancer patients during bone marrow transplantation [PDF]

open access: yes, 2006
The objective was to evaluate the nutritional metabolic profiles in children and adolescents with cancer undergoing bone marrow transplants. Eighteen bone marrow transplantation patients were prospectively evaluated from October 2003 to August 2004.
Garófolo, Adriana   +4 more
core   +2 more sources

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