Results 91 to 100 of about 6,613,174 (344)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Non-equilibrium transport response from equilibrium transport theory [PDF]

open access: yes, 2012
We propose a simple scheme that describes accurately essential non-equilibrium effects in nanoscale electronics devices using equilibrium transport theory.
Ferrer, J., García-Suárez, V. M.
core   +2 more sources

TRANSPORT INFRASTRUCTURE OF UKRAINE: THE MODERN REALITIES AND DEVELOPMENT PROSPECTS

open access: yesBaltic Journal of Economic Studies, 2017
The purpose of the article is to conduct a complex research of the state of transport structure of Ukraine and substantiate prospects of its development. The developed transport system and corresponding infrastructure are a guarantee of high level of the
Tetiana Stroiko, Vitaly Bondar
doaj  

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Author-index [PDF]

open access: yes, 1990
Podeu consultar la versió en castellà a:http://hdl.handle.net/11703 ...
Autoritat del Transport Metropolità
core   +5 more sources

Ștampile noi de amfore grecești descoperite în așezările de la Moșneni și Dulcești (jud. Constanța) [PDF]

open access: yesPeuce, 2020
This article brings additional information to the previous reports on the amphora stamps discovered and published by the authors in various publications in the country and abroad, regarding the new amphora stamps found both in the area of ancient ...
Natalia MATEEVICI, Mihai IONESCU
doaj  

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Changes over time in population level transport satisfaction and mode of travel: a 13 year repeat cross-sectional study, UK [PDF]

open access: yes, 2017
Aim: The aim of the study was to examine changes over time in satisfaction with usual transport mode, explore individual and area level characteristics as mediators in the likelihood of transport satisfaction, and whether any changes in transport ...
Ellaway, Anne   +2 more
core   +1 more source

Timbres amphoriques de Tomis (39 Strada Revoluției) [PDF]

open access: yesPeuce, 2020
The aim of the present article is to publish amphora stamps found during recent archaeological research in Tomis, on the western shore of the Black Sea, focusing this time on stamps found in 2006.
Alexandra LIȚU, Laurențiu CLIANTE
doaj  

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

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