Results 51 to 60 of about 1,759,669 (249)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

A population-based study of neonatal air transport in the Arctic region of Norway from 1994 to 2023

open access: yesFrontiers in Pediatrics
Background and aimsRegionalized centralization of moderate and high-risk pregnancies is essential, but a well-organized postnatal transport service is equally important.
Lene Nymo Trulsen   +7 more
doaj   +1 more source

Technology of ICN Trains on Croatian Railway Lines

open access: yesPromet (Zagreb), 2006
The rolling stock of the Croatian Railways (HZ) for thepassenger transport has reached a very low point of reliability,which for the moment still guarantees travelling safety.
Miroslav Puljiz   +2 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Sectoral features in the management of personnel potential of transport enterprises

open access: yesВісник Житомирського державного технологічного університету: Серія: економіка, управління та адміністрування, 2019
Modern transformations of socio-economic systems require the revision of existing methods and ways of managing them. This process acquires a particular relevance regarding a human factor, which, at this stage of development, becomes crucial in the ...
V.V. Smachylo
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Some remarks on a mathematical model for water flow in porous media with competition between transport and diffusion

open access: yesActa Polytechnica
The contribution deals with the mathematical modelling of fluid flow in porous media, in particular water flow in soils, with the aim of describing the competition between transport and diffusion.
Judita Runcziková   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Reshaping the anomalous Hall response in tilted 3D system with disorder correction

open access: yesNew Journal of Physics
The anomalous Hall conductivity (AHC) in the nodal line semimetals (NLSMs) due to the presence of a symmetry-protected nodal ring adds complexity in the investigation of their transport properties.
Vivek Pandey, Pankaj Bhalla
doaj   +1 more source

Home - About - Disclaimer - Privacy