Results 31 to 40 of about 73,715 (300)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

CONDITIONS OF OVERSIZE CARGO TRANSPORT [PDF]

open access: yesScientific Journal of Silesian University of Technology. Series Transport, 2019
The transport of oversize cargo is distinguished by its specificity on the market of transport services. Specialised equipment is required for its implementation, and the number of people involved in the transport process itself is much higher than in ...
Elżbieta MACIOSZEK
doaj   +1 more source

Digitalization in the single transport space of the EAEU

open access: yesПутеводитель предпринимателя, 2022
The phenomenon of digitalization contributes to the implementation of the strategic national goals of states and international associations. The members of the Eurasian Economic Union form a single digital space of the EAEU, implement the processes of ...
A. M. Novozhilov
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Article 47(2) of the Rotterdam Rules: Solution of old problems or a new confusion?

open access: yesPoredbeno Pomorsko Pravo, 2013
The Rotterdam Rules, adopted by UNCITRAL in 2008, address a number of issues that have not been regulated by previous international conventions, such as the delivery of goods and the right of control.
Časlav Pejović
doaj  

The Impact of Digitization Transport Documents on the Competitiveness of Road Freight Transport Companies

open access: yesLogistics
Background: The rapid digital transformation in logistics requires the adaptation of transport companies to electronic information management, particularly through the implementation of electronic consignment notes (e-CMR).
Miloš Poliak, Dominika Rovňaníková
doaj   +1 more source

Air Transport of Explosives – Modern Solutions

open access: yesSafety & Defense, 2018
The paper is an introduction into the area of hazardous materials transportation. It includes the description of hazardous materials, classification of hazardous materials, and the list of documents necessary for organizing transport of such materials ...
Herc Kamila, Zakrzewska Barbara
doaj   +1 more source

Delivery Times and Delay in Delivery of Consignment under the Conditions of International Carriage

open access: yesCommunications, 2021
Delivery time means a certain period in which the carrier is obliged to transport the consignment from one place to another. The delay occurs when the carrier does not deliver the consignment to the consignee within this period.
Jarmila Sosedová   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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