Results 161 to 170 of about 1,627,601 (317)

Computation Transport Phenomena in Chemical Engineering. Oxidation Resistance of C/C Composites Coated by SiC in Premixed Methane-Air Combustion.

, 1997
Takeshi Kachi, Noriyuki Kobayashi, Norio Arai, Yoshinari Kato, Kinya Kakamu   +4 more
openalex   +2 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Engineering Controllable Myosin Motors for Bidirectional Transport [PDF]

, 2011
Lu Chen, Muneaki Nakamura, Tony D. Schindler, Zev Bryant   +3 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Computation Transport Phenomena in Chemical Engineering. Experiment and Numerical Simulation on the Effect of Solvent on Styrene Polymerization Process Using a Laminar Tubular Reactor.

, 1997
Tohru Nagasako, Manabu Shimada, Kazuhiko Katayama, Kikuo Okuyama   +3 more
openalex   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Integration of co-culture and transport engineering for enhanced metabolite production. [PDF]

Plant Biotechnol (Tokyo)
Yamada Y, Urui M, Shitan N.
europepmc   +1 more source

In vitro models of tumor vessels and matrix: Engineering approaches to investigate transport limitations and drug delivery in cancer [PDF]

, 2013
Bo Ri Seo, Peter DelNero, Claudia Fischbach   +2 more
openalex   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Application of precision mechanical engineering techniques to the design of a moderate energy beam transport for the FAA explosive detection system

, 2002
R.E. Lujan, Kirsten E. Christensen
openalex   +2 more sources