Results 61 to 70 of about 492,514 (296)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Transport Problems – региональный научный журнал, способствующий глобальному информированию

open access: yes, 2019
Brief presentation of Transport Problems scientific journal.Published since 2006, minimal number of issues per year: 4. Average annual number of articles: 65.Publisher: Silesian University of Technology, Poland.
А. Сладковски   +1 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Public transport sector driver behaviour : measuring recklessness using speed and acceleration [PDF]

open access: yes, 2014
Conferende theme: Leading transport into the futurePlease cite as follows:Zeeman, A. S. & Booysen, M. J. 2014. Public transport sector driver behaviour: Measuring recklessness using speed and acceleration paper delivered at the 33rd annual Southern ...
Booysen, M.J.   +3 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Defended Doctoral Dissertation [PDF]

open access: yesTransport, 2008
Information about defended Doctoral Disseration in 2007 is presented. Scientific work (research field - transport engineering) is defended in Vilnius Gediminas Technical University.
M. Česnauskis
doaj   +2 more sources

Method to Use Transport Microsimulation Models to Create Synthetic Distributed Acoustic Sensing Datasets

open access: yesApplied Sciences
This research introduces a new method for creating synthetic Distributed Acoustic Sensing (DAS) datasets from transport microsimulation models. The process involves modeling detailed vehicle interactions, trajectories, and characteristics from the PTV ...
Ignacio Robles-Urquijo   +7 more
doaj   +1 more source

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