Results 71 to 80 of about 566 (219)

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung   +19 more
wiley   +1 more source

Wkład Władysława Górskiego w prace Zespołu Prawa Cywilnego Materialnego Komisji Kodyfikacyjnej PRL

open access: yes, 2021
The input of Władysław Górski into the work of the Substantive Civil Law Team of the Codification Commission of the People’s Republic of Poland The aim of the article is to describe the influence of an outstanding scientist Władysław Górski on the work ...
Dolata, Tomasz
core  

Contracts of cariage of goods by sea with reference to the excluded perils liability of carrier

open access: yes, 2020
Unutar pomorskog prava postoji više međunarodnih konvencija koje reguliraju ugovor o prijevozu stvari morem kao i odgovornost prijevoznika. Republika Hrvatska je potpisnica Konvencije o izjednačenju nekih pravila o teretnici iz 1924.
Mićin, Stipe
core   +2 more sources

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

Institution of shipping

open access: yes, 2016
Freight Forwarding The content of this thesis is a treatise on the issue of freight forwarding contract conclusion as well as on the topic of freight forwarding in general, namely in the context of Czech laws together with the laws of Germany and Austria.
Dudík, Jan
core  

ANALISA MENGGUNAKAN METODE FAILURE MODE AND EFFECT ANALYSIS (FMEA) DALAM KEGAGALAN PROSES BONGKAR MUAT PADA PERUSAHAAN LOGISTIK

open access: yes
This research was conducted at a logistics service company located in Surabaya and engaged in freight forwarding or commonly referred to as ship cargo expeditions. This logisticsservice company also acts as a Logistics Service Provider (LSP) with several
Devi, Yesica Novrita   +2 more
core   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou   +12 more
wiley   +1 more source

Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method

open access: yesAdvanced Science, EarlyView.
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas   +10 more
wiley   +1 more source

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