Results 41 to 50 of about 310,361 (343)

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

METHODS OF PROMOTING INTERMODAL TRANSPORT DEVELOPMENT IN THE FEDERAL REPUBLIC OF GERMANY, FRANCE AND ITALY IN YEARS 1990-2016 ‒ CONCLUSIONS FOR POLAND [PDF]

Transport Problems, 2019
The purpose of this paper is to show directions for promoting alternative modes of transport in Europe and Poland in order to limit the dynamic growth of road transport.
Leszek MINDUR, Marcin PAWĘSKA
doaj   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Using the Min/Max Method for Replenishment of Picking Locations

Transport and Telecommunication, 2017
The irregularity of removing quantities from a definite picking location in a warehouse very often results in the stock out in the particular picking address.
Apsalons Raitis, Gromov Gennady
doaj   +1 more source

Flexible Sensor Network Reprogramming for Logistics [PDF]

, 2007
Besides the currently realized applications, Wireless Sensor Networks can be put to use in logistics processes. However, doing so requires a level of flexibility and safety not provided by the current WSN software platforms.
Evers, L., Havinga, P.J.M., Kuper, J.
core   +7 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Automated Road Milling Cutter for Repair of the Road Surfaces with Variable Trackage

Communications, 2023
The article presents a method of experimental research and created stand with metrological equip-ment that allows to simulate the complex process of milling asphalt concrete samples by force and coordinate closure. As a result of the research, regression
Nurbol Kamzanov, Marzhana Amanova, Aigyl Baikenzheyeva, Guldariya Naimanova, Rustem Kozbagarov   +4 more
doaj   +1 more source

Strategic directions of transport and logistics to ensure the implementation of new industrialization processes [PDF]

, 2019
Ensuring the processes of industrialization of the modern economy requires the formation of an efficient transport and logistics infrastructure. The solution of this task is carried out using the tools of strategic management, in particular the formation
Morkonosov, A. G., Ogorodnikova, E. S., Semenet, I. I., Sidorenko, A. M.   +3 more
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source