Results 21 to 30 of about 564,689 (244)
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
The technological model of operating area by the combined transport [PDF]
The contribution deals with design technology service model using the combined transport. It assesses the performance indicators in relation to price and quality of services provided and on this basis decides on the type of the transport.
Cempírek, Václav+2 more
core +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
The Home Market Effect and Bilateral Trade Patterns [PDF]
We test for home-market effects using a difference-in-difference gravity specification. The home-market effect is the tendency for large countries to be net exporters of goods with high transport costs and strong scale economies.
Chong Xiang, Gordon H. Hanson
core +3 more sources
The Exchange Value Embedded In A Transport System [PDF]
This paper shows that a well designed transport system has an embedded exchange value by serving as a market for potential exchange between consumers. Under suitable conditions, one can improve the welfare of consumers in the system simply by allowing ...
Xia, Qinglan, Xu, Shaofeng
core +2 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
TRANSPORTATION OF PERISHABLE GOODS ON RAILWAYS.
Railway transport is part of the transport system of our country forming the basis and a leading place in the unified transport system occupies The role of the railway in the power of the state, national economy and defense is important. Transportation of the population and the national economy fully meet all the needs, transportation is high quality ...
Usmonov Otabek Ilxomjon o'g'li+1 more
openaire +2 more sources
Improving Safety of Transportation of Dangerous Goods by Railway Transport [PDF]
The transport of dangerous goods by rail carries a high risk of accident and every effort should be made to ensure that such transport is carried out under the best possible safety conditions. The research objective was to analyze and identify the main risks associated with the transport of dangerous goods by rail as well as to identify and assess the ...
openaire +4 more sources
Redesigning A Trolley for The Stairs Building Based on Material Aspect [PDF]
In Bandung, some buildings have three levels or more with no escalator and elevator for their daily needs in moving goods. One example is the Telkom University dormitory.
Fajriati, N. (Ninda )+2 more
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