Results 61 to 70 of about 56,064 (322)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Transport Documents in Carriage of Goods by Sea: International Law and Practice : [book review]

open access: yesPoredbeno Pomorsko Pravo, 2022
From the text: ''The book entitled Transport Documents in Carriage of Goods by Sea: International Law and Practice, written by Časlav Pejović, was published in 2020 by Informa Law from Routledge.
Vesna Skorupan Wolff
doaj  

THE IMPROVEMENT OF HAZARDOUS GOODS TRANSPORTATION TECHNOLOGY

open access: yesTRANSPORT, 2004
This article analyses the conception of the improvement of hazardous goods transportation technology as well as its theoretical principles. Basic organizational aspects of hazardous goods safe transportation are also represented. Effective and safe hazardous goods transportation is possible only using good informational supply.
openaire   +6 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

The Evolution of Romanian Transport within the East European Transport

open access: yesEIRP Proceedings, 2009
Transport services can be considered as being an active part of economy in anycountry. If, until recently, they were considered to be non-productive activities, in the presentservices’ activities contribute substantially to the actualization of GDP.
Laura Olteanu, Krájnik Izabella
doaj  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Welke plaats voor de haven- en logistieke activiteiten in Brussel?

open access: yesBrussels Studies, 2017
Logistics activities are an essential part of the urban economy. In the Brussels-Capital Region, this sector is concentrated in the canal area, as a supplement to port activities carried out there.
Mathieu Strale
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Air transport of dangerous goods

open access: yesTransportation Overview - Przeglad Komunikacyjny, 2016
The article describes the system of creating legal regulations concerning the rules and conditions relating to the carriage of dangerous goods in various fields of transport: by air, sea, land (road, rail, inland waterways). The first and the second parts show the development system of the regulations.
openaire   +1 more source

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