Results 111 to 120 of about 871,856 (304)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Unveiling the Doping- and Temperature-Dependent Properties of Organic Semiconductor Orthorhombic Rubrene from First Principles

Solids
Due to its large hole mobility, organic rubrene (C42H28) has attracted research questions regarding its applications in electronic devices. In this work, extensive first-principles calculations are performed to predict some temperature- and doping ...
Israel Oluwatobi Olowookere, Paul Olufunso Adebambo, Ridwan Olamide Agbaoye, Abdulrafiu Tunde Raji, Mopelola Abidemi Idowu, Stephane Kenmoe, Gboyega Augustine Adebayo   +6 more
doaj   +1 more source

Delocalized carriers and the electrical transport properties of n-type GeSe crystals

, 2019
Recent discovery of a high thermoelectric figure of merit in n-type SnSe single crystal stimulates further research on the analogue compounds. In this work, n-type GeSe is predicted to have a significantly higher normalized power factor along the cross ...
CUI, J, He, J, Chen, Y
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Geomechanical Integrity of Offshore Oil Reservoir During EOR-CO₂ Process: A Case Study

Energies
The aim of this work was to investigate the evolution of the mechanical integrity of the selected offshore oil reservoir during its life cycle. The geomechanical stability of the reservoir formation, including the caprock and base rock, was investigated ...
Piotr Ruciński
doaj   +1 more source

Multiple quasiparticle Hall spectroscopy investigated with a resonant detector

New Journal of Physics, 2014
We investigate the finite frequency (FF) noise properties of edge states in the quantum Hall regime. We consider the measurement scheme of a resonant detector coupled to a quantum point contact in the weak-backscattering limit. A detailed analysis of the
D Ferraro, M Carrega, A Braggio, M Sassetti   +3 more
doaj   +1 more source

Fabrication and ab initio study of downscaled graphene nanoelectronic devices [PDF]

, 2012
In this paper we first present a new fabrication process of downscaled graphene nanodevices based on direct milling of graphene using an atomic-size helium ion beam. We address the issue of contamination caused by the electron-beam lithography process to
Marek E. Schmidt, Harvey N. Rutt, Moktadir, Zakaria, Tsuchiya, Yoshishige, Manoharan Muruganathan, Shuojin Hang, Darren M. Bagnall, Harold Chong, Hiroshi Mizuta, Kalhor, Nima, Chi, Dam Hieu, Cuong, Nguyen Tien, Boden, Stuart A., Chong, Harold, Mizuta, Hiroshi, Rutt, Harvey N., Dam Hieu Chi, Schmidt, Marek E., Stuart A. Boden, Zakaria Moktadir, Nima Kalhor, Yoshishige Tsuchiya, Bagnall, Darren M., Muruganathan, Manoharan, Nguyen Tien Cuong, Otsuka, Nobuo, Nobuo Otsuka, Hang, Shuojin   +27 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Electro-diffusive transport in macroscopic porous media: Estimation of effective transport properties using numerical upscaling

, 2013
In engineering approaches, the electro-diffusive transport behavior of ions through charged porous media is often described by phenomenological theories, formulated on the observation scale of the macroscopic material, without considering the underlying ...
Pivonka, P., Pivonka, Peter, Scheiner, S., Smith, D. W., Scheiner, Stefan, Smith, David W.   +5 more
core   +1 more source