Results 41 to 50 of about 8,188,307 (287)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Plasma self-driven current in tokamaks with magnetic islands

Nuclear Fusion
Magnetic island perturbations may cause a reduction in plasma self-driven current that is needed for tokamak operation. A novel effect on tokamak self-driven current revealed by global gyrokinetic simulations is due to magnetic-island-induced 3D electric
W.X. Wang, M.G. Yoo, E.A. Startsev, S. Kaye, S. Ethier, J. Chen   +5 more
doaj   +1 more source

Transport properties of supercritical methane

Physical Review E
The experimental results on molecular diffusion in supercritical methane in a wide pressure range reported by [U. Ranieri et al., Nat. Commun. 15, 4142 (2024)2041-172310.1038/s41467-024-47961-7] are compared with the theoretical expectations based on the Lennard-Jones model. In the low-pressure low-density limit, the kinetic approach within the Chapman-
Khrapak, Sergey, Formisano, Ferdinando, Bove, Livia   +2 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Enhancement of Proton Transport in an Oriented Polypeptide Thin Film [PDF]

, 2013
Proton transport properties of a partially protonated poly(aspartic acid)/sodium polyaspartate (P-Asp) were investigated. A remarkable enhancement of proton conductivity has been achieved in the thin film. Proton conductivity of 60-nm-thick thin film
Matsui, Jun, Miyashita, Tokuji, Yugami, Hiroo, Nagao, Yuki, Hiramatsu, Hirotsugu, Hitoshi Yamamoto, Tokuji Miyashita, Hirotsugu Hiramatsu, Hiroo Yugami, Yuki Nagao, Takashi Abe, Yamamoto, Hitoshi, Abe, Takashi, Noriko Sata, Sata, Noriko, Jun Matsui   +15 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The future of interurban passenger transport - bringing citizens closer together: Symposium summary and conclusions. 18th International Symposium on Transport Economics and Policy, Madrid, Spain, 16-18 November 2009 [PDF]

, 2010
The Symposium brought together leading transport researchers from around the world to explore a range of issues under the general theme of 'the future for interurban passenger transport'.
International Transport Forum, OECD
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Higher-harmonic collective modes in a trapped gas from second-order hydrodynamics

New Journal of Physics, 2017
Utilizing a second-order hydrodynamics formalism, the dispersion relations for the frequencies and damping rates of collective oscillations as well as spatial structure of these modes up to the decapole oscillation in both two- and three- dimensional gas
W E Lewis, P Romatschke
doaj   +1 more source