Results 81 to 90 of about 8,188,307 (287)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Strategies to improve the thermoelectric performance of iron silicide-based materials

Science and Technology of Advanced Materials
Iron silicide (β-FeSi2) has attracted considerable interest as a sustainable thermoelectric material due to its abundance, non-toxicity, and environmental compatibility.
Sopheap Sam, Sreypich Say, Kosuke Yamazaki, Hiroshi Nakatsugawa   +3 more
doaj   +1 more source

Evaluation of effectiveness of natural organic compounds removal from water in hybrid processes

Journal of Water and Land Development, 2016
Natural organic matter (Natural Organic Matter – NOM) represents a mixture of diverse chemical structure and different properties. The humic substances constitute an important component of NOM, and they are responsible for water color and taste, also ...
Malczewska Beata
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

(111)-Textured p-Type PbTe Films Grown on Muscovite Mica with High Room-Temperature Hole Mobility

Applied Sciences
AIVBVI semiconductors, particularly lead chalcogenides, remain key materials for mid-wave infrared (MWIR) photodetection due to their narrow bandgap and exceptional carrier transport properties.
Danil Kobtsev, Albert Jarashneli, Nitzan Maman, Jürgen Jopp, Mark Auslender, Zinovy Dashevsky   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Rhenium-Induced Negative Magnetoresistance in Monolayer Graphene

Magnetochemistry
The impact of rhenium doping on the transport properties and electron localization in monolayer graphene was experimentally investigated. In this study, we report the emergence of unsaturated negative magnetoresistance in Re-doped graphene devices, which
Ying Zhang, Jiali You, Weiwei Li, Zijie Huang, Yuxiang Feng, Yuyu Liu, Jing Li   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Improving the practice of cost benefit analysis in transport [PDF]

, 2011
Cost-benefit analysis (CBA) is widely recognized to be helpful, even indispensible, for making good decisions on what transport projects to fund. It essentially aims to figure out which projects offer the best value for money, one of the core criteria ...
International Transport Forum, OECD
core   +1 more source

Unveiling the Doping- and Temperature-Dependent Properties of Organic Semiconductor Orthorhombic Rubrene from First Principles

Solids
Due to its large hole mobility, organic rubrene (C42H28) has attracted research questions regarding its applications in electronic devices. In this work, extensive first-principles calculations are performed to predict some temperature- and doping ...
Israel Oluwatobi Olowookere, Paul Olufunso Adebambo, Ridwan Olamide Agbaoye, Abdulrafiu Tunde Raji, Mopelola Abidemi Idowu, Stephane Kenmoe, Gboyega Augustine Adebayo   +6 more
doaj   +1 more source