Results 11 to 20 of about 1,765,806 (356)

Bile Acids Transporters of Enterohepatic Circulation for Targeted Drug Delivery

Molecules, 2022
Bile acids (BAs) are important steroidal molecules with a rapidly growing span of applications across a variety of fields such as supramolecular chemistry, pharmacy, and biomedicine.
Robin Durník, Lenka Šindlerová, Pavel Babica, Ondřej Jurček   +3 more
doaj   +1 more source

ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation

Journal of Lipid Research, 2015
ApoA-I, the main protein component of HDL, is suggested to be involved in metabolic homeostasis. We examined the effects of Milano, a naturally occurring ApoA-I variant, about which little mechanistic information is available.
Maria Lindahl, Jitka Petrlova, Jonathan Dalla-Riva, Sebastian Wasserstrom, Catarina Rippe, Joan Domingo-Espin, Dorota Kotowska, Ewa Krupinska, Christine Berggreen, Helena A. Jones, Karl Swärd, Jens O. Lagerstedt, Olga Göransson, Karin G. Stenkula   +13 more
doaj   +1 more source

Getting to grips with ammonium

eLife, 2013
A fluorescent sensor that can monitor levels of extracellular ammonium has been made by using a fused green fluorescent protein to detect conformational changes in ammonium transport proteins.
Yi Wang, Jonathan A Javitch
doaj   +1 more source

Mechanistic Regimes of Vibronic Transport in a Heterodimer and the Design Principle of Incoherent Vibronic Transport in Phycobiliproteins [PDF]

, 2018
Following the observation of coherent oscillations in non-linear spectra of photosynthetic pigment protein complexes, particularly phycobilliprotein such as PC645, coherent vibronic transport has been suggested as a design principle for novel light ...
Aspuru-Guzik, Alan, Bennett, Doran I. G., Kreisbeck, Christoph, Maly, Pavel, van Grondelle, Rienk   +4 more
core   +4 more sources

Vesicular protein transport [PDF]

The Pharmacogenomics Journal, 2001
Protein transport and sorting in the secretory and endocytic pathways via vesicles is required for organelle biogenesis, constitutive and regulated secretion and constitutive and regulated endocytosis. It is essential for a multicellular organism and the function of its specialised cell types that the multiple transport and sorting events are highly ...
openaire   +2 more sources

Inositol transport proteins [PDF]

FEBS Letters, 2015
The cyclic polyol myo ‐inositol is a key molecule in many different metabolic pathways among all organisms; in addition, it is fundamental for osmotic balance in the mammalian brain. This review sums up inositol transporters from eukaryotic organisms, elucidating their vital role in ...
openaire   +2 more sources

Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through NUP62, inhibiting host nucleocytoplasmic transport pathways [PDF]

, 2012
The herpes simplex virus ICP27 protein is important for the expression and nuclear export of viral mRNAs. Although several binding sites have been mapped along the ICP27 sequence for various RNA and protein partners including the transport receptor TAP ...
Arnold, Aubert, Bachi, Bonifaci, Braun, Bryant, Chen, Chen, Copeland, Cullen, Darshan, Ellison, Ellison, Escudero-Paunetto, Faria, Fischer, Flach, Fontaine-Rodriguez, Fontoura, Fornerod, Fridell, Gerace, Gruffat, Grüter, Gustin, Gustin, Gustin, Han, Hardwicke, Hernandez, Hiriart, Hofemeister, Hutten, Johnson, Kambach, Koffa, Larralde, Lengyel, Lengyel, Li, Lilley, Long, Macaulay, Malik, Malik, McCarthy, Mears, Mears, Mears, Meyer, Michael, Nelson, Park, Pasdeloup, Pasquinelli, Pearson, Pellet, Petersen, Phelan, Piñol-Roma, Pollard, Pritchard, Rice, Rice, Rice, Rice, Rojas, Saavedra, Sandri-Goldin, Satterly, Schmitt, Sekulovich, Siomi, Smith, Soliman, Soliman, Souki, Strambio-De-Castillia, Strässer, Tsuji, Wagstaff, Wente, Zhi, Zhi   +83 more
core   +3 more sources

Nucleoside Transporter Proteins

Current Vascular Pharmacology, 2009
Concentrative nucleoside transporters (CNT; SLC28) and equilibrative nucleoside transporters (ENT; SLC29) mediate the uptake of natural nucleosides and a variety of nucleoside-derived drugs, mostly used in anticancer therapy. SLC28 and SLC29 families consist in three and four members, respectively, which differ in their substrate selectivity and their ...
Molina-Arcas M, Casado FJ, Pastor-Anglada M   +2 more
openaire   +4 more sources

Importin α3 (KPNA3) Deficiency Augments Effortful Reward-Seeking Behavior in Mice

Frontiers in Neuroscience, 2022
Importin α3 (Gene: Kpna3, the ortholog of human Importin α4) is a member of the importin α family and participates in nucleocytoplasmic transport by forming trimeric complexes between cargo proteins and importin β1.
Yoshiatsu Aomine, Yoshiatsu Aomine, Koki Sakurai, Koki Sakurai, Tom Macpherson, Tom Macpherson, Takaaki Ozawa, Takaaki Ozawa, Yoichi Miyamoto, Yoshihiro Yoneda, Masahiro Oka, Takatoshi Hikida, Takatoshi Hikida   +12 more
doaj   +1 more source

Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects [PDF]

, 2009
Many neurodegenerative diseases exhibit axonal pathology, transport defects, and aberrant phosphorylation and aggregation of the microtubule binding protein tau. While mutant tau protein in frontotemporal dementia and parkinsonism linked to chromosome 17
Falzone, Tomas Luis, Goldstein, Lawrence S. B., Lillo, Concepción, Rodrigues, Elizabeth M., Stokin, Gorazd B., Westerman, Eileen L., Williams, David S.   +6 more
core   +1 more source