Results 201 to 210 of about 1,765,806 (356)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Role of intraflagellar transport protein IFT140 in the formation and function of motile cilia in mammals. [PDF]

Cell Mol Life Sci
Yap YT, Pan J, Xu J, Yuan S, Niu C, Zheng C, Li W, Zhou T, Li T, Zhang Y, Holtzman MJ, Pazour GJ, Hess RA, Kelly CV, Touré A, Brody SL, Zhang Z.   +16 more
europepmc   +1 more source

Binding of viral nuclear localization signal peptides to importin-α nuclear transport protein. [PDF]

Biophys J, 2023
Delfing BM, Laracuente XE, Olson A, Foreman KW, Paige M, Kehn-Hall K, Lockhart C, Klimov DK.   +7 more
europepmc   +1 more source

Differential arrest of secretory protein transport in cultured rat hepatocytes by azide treatment. [PDF]

, 1988
R. B. R. Persson, E Ahlström, E Fries
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Biological properties and genomic analysis of the fourth strain of molliviruses encoding a eukaryotic-like transmembrane transport protein. [PDF]

Virol J
Xia Y, Su B, Ren H, Liu F, Cai L, Wong YH, Zhang R.   +6 more
europepmc   +1 more source

A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia

, 2021
Tooba Quidwai, Jiaolong Wang, Emma A Hall, Narcis A Petriman, Weihua Leng, Petra Kiesel, Jonathan N Wells, Laura C Murphy, Margaret A Keighren, Joseph A Marsh, Esben Lorentzen, Gaia Pigino, Pleasantine Mill   +12 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Genome-Wide Identification and Expression Profiling of Sugar Transport Protein Response to Fusarium Head Blight in Wheat (<i>Triticum aestivum</i> L.). [PDF]

Plants (Basel)
Liu Y, Sha J, Zhang S, Sun Y, Hu Z, Ma H, Ma H.   +6 more
europepmc   +1 more source

AI-Based Homology Modelling of Fatty Acid Transport Protein 1 Using AlphaFold: Structural Elucidation and Molecular Dynamics Exploration. [PDF]

Biomolecules, 2023
Acharya R, Shetty SS, Pavan G, Monteiro F, Munikumar M, Naresh S, Kumari NS.   +6 more
europepmc   +1 more source