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We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
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Neurochemical Research, 2017
Zinc, which is involved in the structure of all enzyme classes, is a micro nutrient element and necessary for growth and development. The ability of zinc to function without causing toxic effects is depends on the protection of its homeostasis. Zinc transporter proteins are responsible for keeping zinc at certain concentrations.
Abdulkerim Kasim, Baltaci, Kemal, Yuce
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Zinc, which is involved in the structure of all enzyme classes, is a micro nutrient element and necessary for growth and development. The ability of zinc to function without causing toxic effects is depends on the protection of its homeostasis. Zinc transporter proteins are responsible for keeping zinc at certain concentrations.
Abdulkerim Kasim, Baltaci, Kemal, Yuce
openaire +2 more sources
Bicarbonate transport proteins
Biochemistry and Cell Biology, 2002Bicarbonate is not freely permeable to membranes. Yet, bicarbonate must be moved across membranes, as part of CO2 metabolism and to regulate cell pH. Mammalian cells ubiquitously express bicarbonate transport proteins to facilitate the transmembrane bicarbonate flux.
Deborah, Sterling, Joseph R, Casey
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Cellular and Molecular Life Sciences, 2006
The plasma membrane of epithelial cells and hepatocytes is divided into two separate membrane compartments, the apical and the basolateral domain. This polarity is maintained by intracellular machinery that directs newly synthesized material into the correct target membrane.
D, Delacour, R, Jacob
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The plasma membrane of epithelial cells and hepatocytes is divided into two separate membrane compartments, the apical and the basolateral domain. This polarity is maintained by intracellular machinery that directs newly synthesized material into the correct target membrane.
D, Delacour, R, Jacob
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Science Signaling, 2013
Animated lessons describe the classes of transport proteins and illustrate mechanisms of transport.
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Animated lessons describe the classes of transport proteins and illustrate mechanisms of transport.
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Journal of Membrane Biology, 2009
Transport through lipids and aquaporins is osmotic and entirely driven by the difference in osmotic pressure. Water transport in cotransporters and uniporters is different: Water can be cotransported, energized by coupling to the substrate flux by a mechanism closely associated with protein.
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Transport through lipids and aquaporins is osmotic and entirely driven by the difference in osmotic pressure. Water transport in cotransporters and uniporters is different: Water can be cotransported, energized by coupling to the substrate flux by a mechanism closely associated with protein.
openaire +3 more sources
2002
Publisher Summary This chapter discusses the process of nuclear protein transport. Work on the mechanism of nuclear transport has led to a fairly detailed understanding of how proteins are targeted for import or export. This work has changed the way in which researchers need to think about potential transport mechanisms for their own protein of ...
Marc, Damelin +2 more
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Publisher Summary This chapter discusses the process of nuclear protein transport. Work on the mechanism of nuclear transport has led to a fairly detailed understanding of how proteins are targeted for import or export. This work has changed the way in which researchers need to think about potential transport mechanisms for their own protein of ...
Marc, Damelin +2 more
openaire +2 more sources
Membrane Transport of Proteins
Nature New Biology, 1972FACILITATED diffusion of small organic molecules across cell membranes is thought to be carrier-mediated in part because the process displays reaction kinetics. Models describing carrier transport assume that the transported molecule is associated with the membrane, reacting presumably with membrane proteins, and is then moved across the barrier.
C, Liebow, S S, Rothman
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