Results 91 to 100 of about 1,762,603 (292)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Full-scale tests on horizontal cyclic bearing capacity of cement-soil-improved piles

Yantu gongcheng xuebao
The cement-soil mixing columns are used to improve the surrounding soils of drilled cast-in-place piles in a typical saturated silt site in Suqian City. The full-scale horizontal cyclic loading tests on the cast-in-place piles on site are conducted.
YANG Songsong 1, 2, ZHANG Dingwen 1, 2, ZENG Biao 1, 2, ZHANG Aijun 3, CHENG Chaoheng 3, HE Ling 4
doaj   +1 more source

Models and applications of Optimal Transport in Economics, Traffic and Urban Planning

, 2009
Some optimization or equilibrium problems involving somehow the concept of optimal transport are presented in these notes, mainly devoted to applications to economic and game theory settings.
Santambrogio, Filippo
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

TECHNICAL FEATURES OF RIGGED YACHT BY CATEGORIES AND CLASSES

Aktualʹnì Problemi Rozvitku Ekonomìki Regìonu, 2016
The article is directed on the deeply meaningful scientific study and structural analysis of the technical features of the rigged world modern yachts to pass sailing regattas in different navigation areas.
Svitlana Yeroshkina
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

MPET²: a multi-network poroelastic and transport theory for predicting absorption of monoclonal antibodies delivered by subcutaneous injection. [PDF]

Drug Deliv, 2023
Wang H, Hu T, Leng Y, de Lucio M, Gomez H.   +4 more
europepmc   +1 more source

Transport properties of diluted magnetic semiconductors: Dynamical mean field theory and Boltzmann theory

, 2005
The transport properties of diluted magnetic semiconductors (DMS) are calculated using dynamical mean field theory (DMFT) and Boltzmann transport theory.
E. H. Hwang, K. Hirakawa, N. Furukawa, S. Das Sarma, S. Das Sarma   +4 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Co-optimizing electric bus dispatching and charging considering limited resources and battery degradation

Multimodal Transportation
This paper aims to formulate a mathematical model for a multi-type electric bus scheduling problem to determine the optimal fleet composition, bus-to-trip assignment, and partial charging schedule, where the battery degradation, nonlinear charging, and ...
Chenming Niu, Qiuzi Chen, Ran Tu, Di Huang, Yujian Ye   +4 more
doaj   +1 more source