Results 81 to 90 of about 1,761,291 (295)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Identification of Prior Factors Influencing the Mode Choice of Short Distance Travel

open access: yesDiscrete Dynamics in Nature and Society, 2015
Short distance trips are defined as any trips shorter than or equal to 5 kilometers, which have been found to be a big contributor to the traffic congestion problem.
Ming Li, Guohua Song, Ying Cheng, Lei Yu
doaj   +1 more source

Introduction to Optimal Transport Theory

open access: yes, 2009
These notes constitute a sort of Crash Course in Optimal Transport Theory. The different features of the problem of Monge-Kantorovitch are treated, starting from convex duality issues. The main properties of space of probability measures endowed with the
Santambrogio, Filippo
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relativistic transport theory [PDF]

open access: yesAnnals of Physics, 1966
Abstract A general-relativistic form of the Boltzmann transport equation is developed for particles or radiation interacting with an external medium. Thus generalized, the equations can be used to study radiative transfer in strong, time-varying gravitational fields.
openaire   +2 more sources

Bulk viscous cosmology with causal transport theory

open access: yes, 2011
We consider cosmological scenarios originating from a single imperfect fluid with bulk viscosity and apply Eckart's and both the full and the truncated M\"uller-Israel-Stewart's theories as descriptions of the non-equilibrium processes.
A. Avelino   +21 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Fluctuations and correlations from microscopic transport theory [PDF]

open access: yes, 2009
The multiplicity fluctuations in A+A collisions at SPS and RHIC energies are studied within the HSD transport approach. We find a dominant role of the fluctuations in the nucleon participant number for the final fluctuations. In order to extract physical
Bratkovskaya, Elena L.   +3 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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