Results 141 to 150 of about 967,535 (307)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Transport variability of the Canary Current

, 2014
A Corrente das Canárias pode ser dividida num ramo principal que flui através do arquipélago das Canárias e um ramo secundário que flui entre as ilhas mais orientais das Canárias e entre a costa noroeste de África. Para estudar a variabilidade do transporte de volume de água da Corrente das Canárias, os dados CTD e LADCP de vários cruzeiros RAPROCAN ...
Carmo-Costa, T.M., Hernández-Guerra, A. (Alonso), Comas-Rodríguez, I. (Isis), Pérez-Hernández, M.D. (María Dolores), Vélez-Belchí, P. (Pedro), Fraile-Nuez, E. (Eugenio)   +5 more
openaire   +4 more sources

Value of transport variability for freight transport

, 2013
Rapporten är ett första steg i att finna hur man ska värdera transportosäkerhet för godstransporter. I rapporten presenteras metodik för hur man kan identifiera vilka kostnader som är förknippade med osäkerhet i transporttid.
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Corrigendum: Detecting Change in the Indonesian Seas

Frontiers in Marine Science, 2019
Janet Sprintall, Arnold L. Gordon, Susan E. Wijffels, Ming Feng, Ming Feng, Shijian Hu, Shijian Hu, Ariane Koch-Larrouy, Ariane Koch-Larrouy, Helen Phillips, Dwiyoga Nugroho, Dwiyoga Nugroho, Asmi Napitu, Kandaga Pujiana, R. Dwi Susanto, R. Dwi Susanto, Bernadette Sloyan, Bernadette Sloyan, Beatriz Peña-Molino, Beatriz Peña-Molino, Dongliang Yuan, Dongliang Yuan, Nelly Florida Riama, Siswanto Siswanto, Anastasia Kuswardani, Zainal Arifin, A'an J. Wahyudi, Hui Zhou, Taira Nagai, Joseph K. Ansong, Romain Bourdalle-Badié, Jerome Chanut, Florent Lyard, Brian K. Arbic, Andri Ramdhani, Agus Setiawan   +35 more
doaj   +1 more source

Analysis of in-situ observations in the Strait of Gibraltar [PDF]

, 2002
During the EU-project CANIGO intensive ship-board observations were carried out in April 1996 and October 1997 in order to observe the spatial and temporal variability of the flow, of the internal bore and of the water mass structure in the Strait of ...
Avsic, Tom, Baschek, B., Send, Uwe
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Variability of springtime transpacific pollution transport during 2000–2006: the INTEX-B mission in the context of previous years [PDF]

Atmospheric Chemistry and Physics, 2010
We analyze the transport of pollution across the Pacific during the NASA INTEX-B (Intercontinental Chemical Transport Experiment Part B) campaign in spring 2006 and examine how this year compares to the time period for 2000 through 2006.
G. G. Pfister, L. K. Emmons, D. P. Edwards, A. Arellano, G Sachse, T. Campos   +5 more
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

CATCH 1.4 User's Guide [PDF]

, 2001
The Monte Carlo program CATCH (Capture And Transport of CHarged particles in a crystal) for the simulation of planar channelling in bent crystals is presented.
Biryukov, Valery M.
core   +1 more source