Results 161 to 170 of about 61,413 (308)

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

open access: yesAdvanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong   +6 more
wiley   +1 more source

Summary of final report, contract no. BD543, June 2009 [PDF]

open access: yes
To provide hardware, software, network, systems research, and testing for multi-million dollar trafficoperations, Intelligent Transportation Systems (ITS), and statewide communications investments, theTraffic Engineering and Operations Office has ...
Tung, Leonard J.   +1 more
core  

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

open access: yesAdvanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang   +13 more
wiley   +1 more source

Creating Safe Transportation Options for College Students -- Change Strategies for Safe Transportation Behaviors [PDF]

open access: yes
URI 536162This project took a two-pronged approach to addressing college student drinking and driving. Its initial focus was on providing entertainment and transportation alternatives to University of Rhode Island students,thus emphasizing the harm ...
University of Rhode Island. Transportation Center   +2 more
core  

From Label‐Free Multiphoton Imaging to Pathological Reports: A Vision‐Language Breast Cancer Margin Pathological Diagnosis System

open access: yesAdvanced Science, EarlyView.
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang   +15 more
wiley   +1 more source

Vehicle Sensing and Communications Using LED Headlights To Enhance the Performance of Intelligent Transportation Systems: Proof of Concept, Implementation, and Applications [Supporting Dataset]

open access: yes
69A3551747106National Transportation Library (NTL) Curation Note: As this dataset is preserved in a repository outside U.S. DOT control, as allowed by the U.S.
Ekin, Sabit   +3 more
core  

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