Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Analytical solution for deformation of an existing tunnel induced by shield tunnelling overcrossing in complex strata. [PDF]
Huang K +6 more
europepmc +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Measuring spatial accessibility for wheelchair users: A case study in a Chinese campus. [PDF]
Huang Y +5 more
europepmc +1 more source
Environmental sensitive road planning and transportation techniques in forest engineering
H. Hulusi Acar
openalex +1 more source
Corrigendum to “Developing Transportation Engineering and Planning Metrics for Rural Volunteer Driver Programs” [PDF]
openalex +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Corrigendum to "Skin-inspired phototherapeutic cryogel ameliorates infected wound healing by orchestrating mechanotransduction and immunomodulation" [Bioact. Mater. 57 (2026) 768-790]. [PDF]
Dutta SD +9 more
europepmc +1 more source
Dynamic Calculation and Analysis of the Fee Rate for Safe and Civilized Construction in Railway Transportation Engineering Based on PSO-SVM [PDF]
Yongtao Hu, Hao Ma, Liuya Huang
openalex +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source

