Results 221 to 230 of about 3,698,298 (387)

Investigating the Future of Transportation Engineering Education

, 2019
Meg West, André Carrel
openalex   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Deep learning based predictive models for real time accident prevention in autonomous vehicle networks. [PDF]

Sci Rep
Almutairi A, Al Asmari AF, Alanazi F, Alqubaysi T, Armghan A.   +4 more
europepmc   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

A comparative analysis of nanocoated expanded polystyrene for sustainable infrastructure applications. [PDF]

Sci Rep
Shekib MA, Bakhoum ES, Omran MM, Ahmed AM, Fahim IS, AbdelSalam SS.   +5 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Federated learning with enhanced cryptographic security for vehicular cyber-physical systems. [PDF]

Sci Rep
Babbar H, Rani S, Shabaz M.
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Multiagent Route Choice Game for Transportation Engineering

, 2015
Xuan Di, Henry X. Liu, D. Levinson
semanticscholar   +1 more source

Starfish-inspired tube feet for temporary and switchable underwater adhesion and transportation. [PDF]

Sci Adv
Lee H, Ryu Y, Oh Y, Kim C, Lee Y, Choi H, Kim J, Kim JH, Kang J, Park K, Turner KT, Yang S, Yoon H.   +12 more
europepmc   +1 more source