Results 81 to 90 of about 10,850,245 (311)

Design of REST API for Local Public Transportation Information Services in Malang City

JITeCS (Journal of Information Technology and Computer Science), 2017
.Utilization of information technology in the field of public transportation has been proven in improving the quality of public transportation services.
Agi Putra Kharisma, Aryo Pinandito
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Other title: Overview of the Kansas Department of Transportation Other title: Kansas Department of Transportation Overview Other title: KDOT Overview

, 2011
application/pdf Title supplied by cataloger from Kansas Department of Transportation website. "February 3, 2011." Presentation to the Kansas Legislature, House Transportation Committee, by staff of the Kansas Department of Transportation.Presentation ...
Kansas. Department of Transportation.
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Evaluasi Sistem Informasi Kendaraan (GF Service) di Binus University Berdasarkan Kerangka Cobit pada Domain Delivery and Support

ComTech, 2015
Information Systems Audit is an activity that is carried out in a company that aims to ensure compliance with existing policies. General Services is one of the units in BINUS University whose activities in the form of services such as Transportation and
Tangkas Udiono, Haris Setia Budi, Mariyani Mariyani   +2 more
doaj   +1 more source

Evaluation of transportation alternatives for aging population in the era of self-driving vehicles

IATSS Research, 2020
Objective: Access to transportation is very important for older adults as it allows them to lead an independent and social life. With a growing elderly population, providing access to transportation is one of the greatest societal challenges in the ...
Md Mahmudur Rahman, Shuchisnigdha Deb, Lesley Strawderman, Brian Smith, Reuben Burch   +4 more
doaj   +1 more source

Neonatal transport metrics and quality improvement in a regional transport service

Translational Pediatrics, 2019
Sick neonates in non-tertiary centers rely on the expert skills of neonatal transport teams (NTTs) and efficient systems to provide safe and timely transport to tertiary centers. Quality metrics to measure and compare performance among transport teams are essential to ensure delivery of high-quality care and efficient use of limited and costly ...
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Sentiment Analysis to Improve the Quality of Public Transportation Services "Suroboyo Bus"

Indonesian Interdisciplinary Journal of Sharia Economics
Public transportation is a very important tool in improving and developing the economy of an area. The role of public transportation is very important in supporting mobility or community movement.
Anisa Tri Kumalasari, Wiwik Handayani
doaj   +1 more source