Results 111 to 120 of about 1,598,914 (308)

Intelligent Transportation Systems

, 2002
This paper presents a review of the state of the art on Intelligent Transportation Systems and discuss the problem of modelling and simulation. ITS involves a large number of research ares and, therefore, this paper focus on those we believe to be the most relevant.
Figueiredo, Lino, Jesus, Isabel S., Tenreiro Machado, J. A., Ferreira, José Rui   +3 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Spatio-Temporal Graphs in Transportation: Challenges, Optimization, and Prospects

Systems
Intelligent and information systems in transportation record and accumulate large volumes of raw data on dynamic transportation processes. However, these data are not fully utilized for forecasting, real-time planning, and transportation management ...
Aleksandr Rakhmangulov, Nikita Osintsev, Pavel Mishkurov   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Sleep and task related fatigue in automated vehicles: Measures and countermeasures

Safety and Health at Work, 2022
Stephen Popkin, Donald Fisher
doaj   +1 more source

Enhancing Service Quality of On-Demand Transportation Systems Using a Hybrid Approach with Customized Heuristics

Smart Cities
As customers’ expectations continue to rise, advanced on-demand transport services face the challenge of meeting new requirements. This study addresses a specific transportation issue belonging to dial-a-ride problems, including constraints aimed at ...
Sonia Nasri, Hend Bouziri, Wassila Aggoune Mtalaa   +2 more
doaj   +1 more source

Information measures and cognitive limits in multilayer navigation

, 2015
Cities and their transportation systems become increasingly complex and multimodal as they grow, and it is natural to wonder if it is possible to quantitatively characterize our difficulty to navigate in them and whether such navigation exceeds our ...
Barthelemy, Marc, Gallotti, Riccardo, Porter, Mason A.   +2 more
core   +1 more source

Computer supported estimation of input data for transportation models [PDF]

, 2010
Control and management of transportation systems frequently rely on optimization or simulation methods based on a suitable model. Such a model uses optimization or simulation procedures and correct input data.
Cenek, Petr, Kopf, Marija, Tarábek, Peter   +2 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source