Results 141 to 150 of about 1,598,914 (308)

A Framework for Prioritizing the Connected Vehicle Infrastructure Service in Mixed Autonomy Traffic: A Fuzzy-Analytic Hierarchy Process Approach

open access: yesJournal of Advanced Transportation
This study investigates the integration and prioritization of connected vehicle infrastructure services (CVISs) in mixed autonomy traffic systems using a fuzzy–analytic hierarchy process (Fuzzy–AHP).
Woosuk Kim   +5 more
doaj   +1 more source

Urban transportation: Perspectives on mobility and choice [PDF]

open access: yes
A study of urban transportation systems are presented characterized by intensive scrutiny of many ideas, philosophies, and academic perspectives. This report is intended to communicate some dimensions of the urban transportation problem to the general ...
Arnold, G. R.   +9 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Stable dynamics in transportation systems [PDF]

open access: yes, 2000
We present a new class of transportation systems, the stable dynamics models, which provides a natural link between the static and dynamic trafic network models. They can be seen as steady states of dynamic networks (flows are constant in time). These models turn out to be very easy to study analytically for simple networks.
NESTEROV, Yu, de PALMA, André
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Dynamic model of respiratory infectious disease transmission in urban public transportation systems. [PDF]

open access: yesHeliyon, 2023
Guo Z   +7 more
europepmc   +1 more source

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