Results 161 to 170 of about 66,265 (280)

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

Advanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol, Pascal Benkert, Sabine Schaedelin, Mario Ocampo‐Pineda, Noemi Montobbio, Po‐Jui Lu, Batuhan Ayci, Antonia Wenger, Alfi Aran Shukur, Kornelius Kaim, Lester Melie‐Garcia, Matthias Weigel, Alessio Signori, Pasquale Calabrese, Ludwig Kappos, Maria Pia Sormani, Jens Kuhle, Cristina Granziera   +17 more
wiley   +1 more source

Comparative Analysis of Transposable Element Evolution in Crustaceans. [PDF]

Genome Biol Evol
Zeng X, Zhao W, Kanika NH, Dong Y, Hou X, Chen X, Wang J, Wang C.   +7 more
europepmc   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

TE-SCALE: a comprehensive database for exploring transposable element expression across human cancers at single-cell resolution. [PDF]

Nucleic Acids Res
Meng X, Nie Z, Wang Q, Hu Y, Deng Y, Ai N, Huang Z, Li Y, Yuan Y, Xiao J, Zeng J, Li G, Jiang L.   +12 more
europepmc   +1 more source

Ancestral genome reconstruction enhances transposable element annotation by identifying degenerate integrants

, 2023
Wayo Matsushima, Evarist Planet, Didier Trono   +2 more
openalex   +1 more source

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

Advanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang, Ziwen Gao, Hui Huang, Chanyuan Zhang, Yiquan Tang, Qianhui Qu, Huabin Li, Jing Ke, Zhiji Chen, Menglong Feng, Hu Zhou, Yilai Shu, Wei Yuan   +12 more
wiley   +1 more source

Transposable Element-Derived miR-28-5p and miR-708-5p: Exploring Potential Roles in Lung Cancer. [PDF]

Noncoding RNA
Chira S, Braicu C, Strilciuc S, Calin GA, Berindan-Neagoe I.   +4 more
europepmc   +1 more source

The population genomics of transposable element activation in the highly repressive genome of an agricultural pathogen [PDF]

, 2020
Danilo Pereira, Ursula Oggenfuss, Bruce A. McDonald, Daniel Croll   +3 more
openalex   +1 more source

Structural Variation and 3D Genome‐Driven DNA/RNA Methylation Divergence Contributing to Cotton Fiber Domestication

Advanced Science, EarlyView.
These findings elucidated the crucial role of the “SVs‐3D genome remodeling‐epigenetic modifications‐gene expression” cascade regulatory network in cotton fiber domestication, offering both a theoretical foundation and genetic resources for molecular design breeding in fiber crops.
Lei Shao, Shangkun Jin, Haojie Jiang, Tianyu Pan, Zesheng Rui, Xiaowen Shi, Ting Zhao, Zhanfeng Si, Xueying Guan, Yan Hu, Tianzhen Zhang, Lei Fang   +11 more
wiley   +1 more source

Transposable element dynamics in glioblastoma stem cells: insights from locus-specific quantification. [PDF]

Mob DNA
Pizzagalli MD, Suita Y, Leary OP, Tapinos N.   +3 more
europepmc   +1 more source