Results 161 to 170 of about 2,250,508 (337)

Isolation and characterization of a nematode transposable element from Panagrellus redivivus. [PDF]

, 1987
Christopher D. Link, J Graf-Whitsel, William B. Wood   +2 more
openalex   +1 more source

Enhancing Specificity, Precision, Accessibility, Flexibility, and Safety to Overcome Traditional CRISPR/Cas Editing Challenges and Shape Future Innovations

Advanced Science, EarlyView.
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi, Mohamed Ramadan, Lu Yu, Fengjiao Hui, Amjad Hussain, Xiaofeng Zhou, Yu Yu, Xianlong Zhang, Shuangxia Jin   +8 more
wiley   +1 more source

Insertion and excision of the transposable element mariner in Drosophila. [PDF]

, 1990
Glenn J. Bryan, Dan Garza, Daniel L. Hartl   +2 more
openalex   +1 more source

A Two‐Protein Chemoreceptor Complex Regulates Oxygen Thresholds in Bacterial Magneto‐Aerotaxis

Advanced Science, EarlyView.
Magnetotactic bacteria align with Earth's magnetic field, helping them migrate toward low‐oxygen environments. This study reveals how Magnetospirillum gryphiswaldense uses a specialized flavin adenine dinucleotide (FAD)‐dependent chemoreceptor, composed of two interacting proteins, for precise navigation in oxygen gradients.
Julian Herz, Carina Weigel, Leonie Scheder, Raz Zarivach, Itay Algov, Yonatan Chemla, Felix Popp, Cornelius Riese, Mohammad A. Charsooghi, Lital Alfonta, Michael M. Meijler, Dirk Schüler, Damien Faivre, Daniel Pfeiffer   +13 more
wiley   +1 more source

DNA modification of a maize transposable element correlates with loss of activity.

, 1986
Vicki L. Chandler, Virginia Walbot
openalex   +1 more source

Identification of a regulatory transposon that controls the Mutator transposable element system in maize. [PDF]

, 1991
Paul Chomet, Damon Lisch, Kristine Hardeman, Vicki L. Chandler, Michael Freeling   +4 more
openalex   +1 more source

Nanoparticle‐Mediated CXCL12–CXCR4 Inhibition Reprograms Macrophages and Suppresses Gastric Carcinoma

Advanced Science, EarlyView.
Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao, Xiaolei Cheng, Rongbin Lv, Dianshui Sun, Jihua Wang, Runjia Fu, Rumei Gong, Yueying Xiao, Qin Liu, Xiaomei Li   +9 more
wiley   +1 more source

Transposition of the maize Ds element from a viral vector to the rice genome [PDF]

, 1994
Kazuhiko Sugimoto, Yoshiaki Otsuki, Shoko Saji, Hirohiko Hirochika   +3 more
openalex   +1 more source

PTf‐SRiApt Targeting SCAF4‐POLR2A Interaction Suppresses Tumor Growth and Promotes Antitumor Immunity in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei, Yichun Pan, Jie Zhai, Tongqing Li, Yuxin Zhou, Sheyu Zhang, Juan Wei, Qian Hu, Xueying Liu, Lu Guo, Weizhu Wu, Yong Wei, Qin Wu, Weihong Tan   +13 more
wiley   +1 more source

HeT-A, a transposable element specifically involved in "healing" broken chromosome ends in Drosophila melanogaster. [PDF]

, 1992
Harald Biessmann, K Valgeirsdóttir, A Lofsky, C. Chin, Bret E. Ginther, Robert Levis, Mary Lou Pardue   +6 more
openalex   +1 more source