Results 191 to 200 of about 66,265 (280)

Transposable Element Is Predictive of Chemotherapy- and Immunotherapy-Related Overall Survival in Glioma. [PDF]

Biomedicines
Peng B, Shen F, Chen Z, Yu Y, Liu R, Zhang Y, Long G, Hu G, Liu Y.   +8 more
europepmc   +1 more source

Compartmentalized Homeostasis Drives High Bamboo Forest Productivity under Nutrient Imbalance

Advanced Science, EarlyView.
This study reveals how Moso bamboo achieves high productivity despite nutrient‐poor soils. It employs a unique strategy, maintaining strict nutrient balance in its leaves while using woody tissues as flexible storage reservoirs. This compartmentalized mechanism buffers the plant from soil phosphorus limitation and microbial competition, resolving the ...
Zhikang Wang, Quan Li, Man Shi, Marcio F.A. Leite, Xinli Chen, Eiko E. Kuramae, Viviane Cordovez, Tingting Cao, Chenglei Zhu, Libin Zhou, Wenjuan Yu, Zhiyao Tang, Changhui Peng, Xinzhang Song   +13 more
wiley   +1 more source

High interferon response signatures in SLE patient leukocytes are associated with increased transposable element expression in gene introns and intergenic regions. [PDF]

Mob DNA
Arteaga-Vazquez LJ, Sepulveda H, Villalobos Reveles B, Suzuki K, Kalunian KC, Ay F, Boothby MR, Rao A.   +7 more
europepmc   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Pangenome analysis of transposable element insertion polymorphisms reveals features underlying cold tolerance in rice. [PDF]

Nat Commun
Qian Y, Zhou Z, Ouyang T, Li D, Li R, Gan P, Qiao R, Tan Y, Qian M, Liu L, Li J, Lu K, Luo J, Chen LL, Song JM.   +14 more
europepmc   +1 more source

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

Advanced Science, EarlyView.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan, Wentao Gong, Xiaodian Cai, Jinyan Teng, Jiali Cai, Haonan Zeng, Wondossen Ayalew, Qingpeng Shen, Zhanming Zhong, Yifei Wang, Wenjing Zhang, Yuhan Tian, Dantong Xu, Yahui Gao, Hongwei Yin, Yuebo Zhang, Jiahui Hou, Tianru Zhou, Jiaqi Li, Lingzhao Fang, Xiaolong Yuan, Zhe Zhang   +21 more
wiley   +1 more source

Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti. [PDF]

BMC Biol
Bergman A, Crist AB, Lopez-Maestre H, Blanc H, Castelló-Sanjuán M, Frangeul L, Varet H, Daron J, Merkling SH, Saleh MC, Lambrechts L.   +10 more
europepmc   +1 more source

Targeted Insertion of the mPing Transposable Element

, 2018
Ashley E. Strother, Stephanie Diaz, Mary E Baker, C. Nathan Hancock   +3 more
openalex   +1 more source

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

Advanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan, Jiating Yu, Jieyi Pan, Fan Yuan, Jiadong Ji, Rusong Zhao, Zhi‐Ping Liu, Bingqiang Liu, Ling‐Yun Wu, Duanchen Sun   +9 more
wiley   +1 more source

A transposable element insertion in AUX/IAA16 disrupts splicing and causes auxin resistance in Bassia scoparia. [PDF]

Plant J
Montgomery JS, Soni N, Marques Hill S, Morran S, Patterson EL, Edwards SA, Ratnayake S, Hung YH, Pandesha PH, Slotkin RK, Napier R, Dayan F, Gaines T.   +12 more
europepmc   +1 more source