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Transposable Elements in Nematodes
1994Transposable elements are present in the genomes of most, if not all, organisms. Because of their ability to insert into and excise from the chromosomes of their hosts transposons are a significant source of spontaneous mutations in organisms. Therefore they can be used as a tool for cloning genes that have been identified by mutations and for which no
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Genetic transformation of Drosophila with transposable element vectors.
Science, 1982Exogenous DNA sequences were introduced into the Drosophila germ line. A rosy transposon (ry1), constructed by inserting a chromosomal DNA fragment containing the wild-type rosy gene into a P transposable element, transformed germ line cells in 20 to 50 ...
G. Rubin, A. Spradling
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Transposable Elements in Spruce
2020Transposable elements (TEs), along with other repetitive sequences, were dismissed for a long time as junk DNA. Over the years, much evidence accumulated, clarifying how TEs are instead major components of host genomes and have a substantial role in shaping genome structure, functioning, and evolution.
Giovanni Marturano +3 more
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Transposable Elements and Their Identification
2012Most genomes are populated by thousands of sequences that originated from mobile elements. On the one hand, these sequences present a real challenge in the process of genome analysis and annotation. On the other hand, there are very interesting biological subjects involved in many cellular processes.
Wojciech Makalowski +3 more
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Nomenclature of transposable elements in prokaryotes
Plasmid, 1979Transposable elements are defined as specific DNA segments that can repeatedly insert into a few or many sites in a genome. They are classified as simple IS elements, more complex Tn transposons and self-replicating episomes. Definitions and nomenclature rules for these three classes of prokaryotic transposable elements are specified.
P. Starlinger +6 more
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Transposable element evolution in mammals
Nature Genetics, 2023C. Anania
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Transposable elements in cancer
Nature Reviews Cancer, 2017Transposable elements give rise to interspersed repeats, sequences that comprise most of our genomes. These mobile DNAs have been historically underappreciated - both because they have been presumed to be unimportant, and because their high copy number and variability pose unique technical challenges. Neither impediment now seems steadfast. Interest in
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1991
Transposable elements were first detected in maize by Barbara McClintock and reported in the 1950s. These were revealed by experiments that were designed for a cytogenetic study involving the short arm of chromosome 9. It was in the progeny of plants undergoing the chromosomal type of breakage—fusion—bridge cycle that a burst of somatic instability and
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Transposable elements were first detected in maize by Barbara McClintock and reported in the 1950s. These were revealed by experiments that were designed for a cytogenetic study involving the short arm of chromosome 9. It was in the progeny of plants undergoing the chromosomal type of breakage—fusion—bridge cycle that a burst of somatic instability and
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Transposable Elements in Yeast
1983Publisher Summary Transposable elements are the DNA sequences that move to new genomic locations at a much higher rate than that of the bulk of the cellular DNA. The ability to cause deletions or chromosomal rearrangements is characteristic of these elements, and many have been shown to affect the expression of chromosomal genes by inserting adjacent
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Transposable elements and psychiatric disorders
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2014Transposable Elements (TEs) or transposons are low‐complexity elements (e.g., LINEs, SINEs, SVAs, and HERVs) that make up to two‐thirds of the human genome. There is mounting evidence that TEs play an essential role in genomic architecture and regulation related to both normal function and disease states.
G. Guffanti +6 more
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