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Transposable Elements and Fitness of Bacteria [PDF]
Theoretical Population Biology, 2002 A stochastic model was designed to describe the evolution of bacterial cultures during 10,000 generations. It is based on a decreasing law for the generation of beneficial mutations as they become fixed in the genomes. Seven beneficial mutations on average were necessary to improve the relative fitness from 1.0 to 1.43 and the model was consistent with
Martiel, Jean-Louis, Blot, Michel
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Evolution of transposable elements
Journal of Antimicrobial Chemotherapy, 1986Transposable elements are at an advantage compared with other DNA sequences. This has led to the generation of transposable systems from a variety of different sources. Once fabricated, these elements can very simply acquire accessory genes, such as those that encode resistance to antibiotics.
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Transposable Elements and Cancer
1986Tumor progression is accompanied by many chromosomal aberrations and DNA rearrangements which contribute to the aggressiveness of the tumor. It is possible that active transposition of DNA elements play a role in these events. Approximately one third of the mammalian genome is composed of repetitive sequences (103 — 105 copies).
E. Arman +3 more
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Transposable Elements in Nematodes
1994Transposable elements are present in the genomes of most, if not all, organisms. Because of their ability to insert into and excise from the chromosomes of their hosts transposons are a significant source of spontaneous mutations in organisms. Therefore they can be used as a tool for cloning genes that have been identified by mutations and for which no
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Genetic transformation of Drosophila with transposable element vectors.
Science, 1982Exogenous DNA sequences were introduced into the Drosophila germ line. A rosy transposon (ry1), constructed by inserting a chromosomal DNA fragment containing the wild-type rosy gene into a P transposable element, transformed germ line cells in 20 to 50 ...
G. Rubin, A. Spradling
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Transposable Elements and Their Identification
2012Most genomes are populated by thousands of sequences that originated from mobile elements. On the one hand, these sequences present a real challenge in the process of genome analysis and annotation. On the other hand, there are very interesting biological subjects involved in many cellular processes.
Wojciech Makalowski +3 more
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Transposable Elements in Spruce
2020Transposable elements (TEs), along with other repetitive sequences, were dismissed for a long time as junk DNA. Over the years, much evidence accumulated, clarifying how TEs are instead major components of host genomes and have a substantial role in shaping genome structure, functioning, and evolution.
Giovanni Marturano +3 more
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Nomenclature of transposable elements in prokaryotes
Plasmid, 1979Transposable elements are defined as specific DNA segments that can repeatedly insert into a few or many sites in a genome. They are classified as simple IS elements, more complex Tn transposons and self-replicating episomes. Definitions and nomenclature rules for these three classes of prokaryotic transposable elements are specified.
P. Starlinger +6 more
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Transposable element evolution in mammals
Nature Genetics, 2023C. Anania
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Transposable elements in cancer
Nature Reviews Cancer, 2017Transposable elements give rise to interspersed repeats, sequences that comprise most of our genomes. These mobile DNAs have been historically underappreciated - both because they have been presumed to be unimportant, and because their high copy number and variability pose unique technical challenges. Neither impediment now seems steadfast. Interest in
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