Results 121 to 130 of about 191,846,196 (274)
ABSTRACT Background To report 5‐year outcomes in a cohort of patients who received anti‐VEGF therapy for macular oedema secondary to central retinal vein occlusion (CRVO) in routine clinical practice. Methods In this retrospective observational study, 593 treatment‐naïve eyes that commenced anti‐VEGF treatment between 1 January 2010, and 2019 were ...
Katrin Rudolph +10 more
wiley +1 more source
Metformin and Severe Post‐COVID‐19 Outcomes Among Individuals With Diabetes Mellitus
ABSTRACT Aims We evaluated the relationship between metformin, one of the most commonly prescribed medications for individuals with diabetes, and COVID‐19 sequelae. Materials and Methods We evaluated a retrospective cohort of individuals in the National Clinical Cohort Collaborative with Type 2 diabetes mellitus and COVID‐19 who were prescribed ...
Zachary B. Dozier +148 more
wiley +1 more source
Performing Large‐Scale Genetic Analysis in the Bleeding Disorders Community
ABSTRACT Inherited bleeding disorders encompass a diverse group of conditions caused by genetic defects affecting coagulation factors, fibrinogen, von Willebrand factor, or platelet function. Despite major advances in quantitative and functional laboratory assays, a substantial diagnostic gap remains, particularly in patients with mild or atypical ...
Anna R. Blankstein +6 more
wiley +1 more source
Comparison of three dose regimens of aprotinin in infants undergoing the arterial switch operation
To determine the most effective dose regimen of aprotinin for infants undergoing arterial switch operation for transposition of the great arteries in reducing blood loss and postoperative packed red blood cell (PRBC) requirements.
Verma Yashwant +5 more
doaj
Transposition complexes refer to hearts in which there is a reversal in the relationship between the ventricles and great arteries, i.e. there is ventriculoarterial discordance.
Sara Thorne, Sarah Bowater
core +1 more source
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto +14 more
wiley +1 more source
Smartphone heart monitors in pediatric CIEDs: A pilot study. Smartphone heart monitors did not induce EMI in children with CIEDs, enabling reliable heart rate measurement and accurate identification of ventricular non‐captures. ABSTRACT Background Portable heart monitors enable on‐demand electrocardiogram (ECG) recordings and enhance symptom‐rhythm ...
Chun‐Lok Ho +3 more
wiley +1 more source
Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah +8 more
wiley +1 more source
The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley +3 more
wiley +1 more source

