Results 191 to 200 of about 207,046 (295)

Diagnostic Pitfall: Mixed Connective Tissue Disease‐Associated Pulmonary Hypertension Presenting With Postpartum Right‐Sided Heart Failure in a 21‐Year‐Old—Case Report

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Mixed connective tissue disease is a multisystem autoimmune condition characterized by overlapping clinical and serological features related to anti‐U1‐RNP antibodies of at least two connective tissue diseases. It may present with myocarditis, pericarditis, pulmonary arterial hypertension, and, less commonly, heart failure.
Sai Santhosha Mrudula Alla   +10 more
wiley   +1 more source

Right Ventricular Dysfunction and Ventriculo‐Arterial Uncoupling in Heart Failure With Preserved Ejection Fraction: A Phenotype‐Specific Review of Mechanisms, Diagnosis, and Therapeutic Strategies

open access: yesClinical Cardiology, Volume 49, Issue 11, November 2026.
Right ventricular dysfunction affects 19%–33% of patients With heart failure With preserved ejection fraction and is associated With exercise intolerance, hospitalization, and mortality. Assessing right ventricular function and its coupling with the pulmonary circulation may improve risk stratification and support management tailored to distinct ...
Amarelle Chamoun   +13 more
wiley   +1 more source

Sphingosine‐1‐Phosphate Attenuates LPS‐Induced Inflammatory Cardiac Injury in Association With RASGRP1–S100A9–NLRP3 Signaling

open access: yesDrug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Lipopolysaccharide (LPS) induces endotoxemia‐associated inflammatory cardiac injury rather than classical viral or autoimmune myocarditis. Sphingosine‐1‐phosphate (S1P) regulates cardiovascular and immune responses, predominantly through S1P receptors, but whether it also modulates macrophage‐associated inflammatory signaling during LPS ...
Chaofu Yue   +15 more
wiley   +1 more source

A Fatal Case of Pulmonary Tumor Thrombotic Microangiopathy Originating From Primary Bladder Adenocarcinoma

open access: yesIJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Pulmonary tumor thrombotic microangiopathy is a rare, fatal complication of malignancy, with few reports involving bladder cancer. Case Presentation An 81‐year‐old man with chronic obstructive pulmonary disease presented with hematuria and progressive exertional dyspnea.
Hiroki Kodani   +5 more
wiley   +1 more source

Liquid Biopsy: Past, Present, and Future

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu   +8 more
wiley   +1 more source

Genetic Insights Into Cardiomyopathy With Restrictive Phenotype: Implications for Diagnosis and Personalized Care

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 11, November 2026.
Among 568 patients with cardiomyopathy, 33 exhibited a restrictive phenotype, including 7 with RCM, 20 with HRCM, and 6 with HDRCM. Pathogenic or likely pathogenic variants were identified in 24 patients (72.7%). Variant carriers had a smaller aortic sinus diameter than non‐carriers (30.79 ± 3.48 vs.
Nianwei Zhou   +11 more
wiley   +1 more source

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