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Vutrisiran for transthyretin amyloidosis. [PDF]

Aust Prescr
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Transthyretin amyloid cardiomyopathy

Medicina Clínica (English Edition), 2021
Transthyretin (TTR) cardiac amyloidosis is a severe, progressive, infiltrative disease caused by the deposition of TTR at cardiac level. It may be due to a genetic alteration in its hereditary form (ATTRv) or as a consequence of an age-related degenerative process (ATTRwt). Thanks to advances in imaging techniques and the possibility of achieving a non-
Pablo, Garcia-Pavia, Fernando, Domínguez, Esther, Gonzalez-Lopez   +2 more
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Wallaby transthyretin

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 1995
A cDNA library was constructed from liver RNA of the Australian diprotodont marsupial Macropus eugenii, the Tammar wallaby. A cloned full-length transthyretin cDNA was sequenced. The derived amino-acid sequence showed 68% overall similarity to that of human transthyretin, with 86% similarity in the thyroxine binding site.
C M, Brack, W, Duan, A J, Hulbert, G, Schreiber   +3 more
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Transthyretin Cardiac Amyloidosis

Current Cardiology Reports, 2017
Transthyretin (TTR)-related cardiac amyloidosis is a progressive infiltrative cardiomyopathy that mimics hypertensive, hypertrophic heart disease and may go undiagnosed. Transthyretin-derived amyloidosis accounts for 18% of all cases of cardiac amyloidosis.
Anit K, Mankad, Keyur B, Shah
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Cardiac transthyretin amyloidosis

Heart, 2012
Cardiac amyloidosis of transthyretin fibril protein (ATTR) type is an infiltrative cardiomyopathy characterised by ventricular wall thickening and diastolic heart failure. Increased access to cardiovascular magnetic resonance imaging has led to a marked increase in referrals to our centre of Caucasian patients with wild-type ATTR (senile systemic ...
Jason N, Dungu, Lisa J, Anderson, Carol J, Whelan, Philip N, Hawkins   +3 more
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Transthyretin-Related and Transthyretin-like Proteins

2009
Bioinformatics programs are highly accurate in identifying protein families directly from protein sequences, even when the sequence identity is very low. The transthyretin-related proteins (TRPs) are one example of a protein family that has been identified.
A. Elisabeth Sauer-Eriksson, Anna Linusson, Erik Lundberg   +2 more
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Hereditary transthyretin amyloidosis associated with a transthyretin variant Thr59Arg

Amyloid, 2017
Hereditary transthyretin (TTR) amyloidosis is characterized by ATTR amyloid deposits in various tissue sites and organs, such as peripheral nerves, heart, gastrointestinal tract, kidneys, eyes, and...
Tetsuya, Watanabe, Konen, Obayashi, Yohei, Misumi, Masayoshi, Tasaki, Satoru, Shinriki, Tomotaka, Ando, Takafumi, Akagami, Mitsuharu, Ueda, Taro, Yamashita, Shinichi, Hirotani, Yukio, Ando   +10 more
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