Standard PK/PD concepts can be applied to determine a dosage regimen for a macrolide: the case of tulathromycin in the calf [PDF]
The pharmacokinetic (PK) profile of tulathromycin, administered to calves subcutaneously at the dosage of 2.5 mg/kg, was established in serum, inflamed (exudate), and noninflamed (transudate) fluids in a tissue cage model. The PK profile of tulathromycin
Aliabadi +35 more
core +4 more sources
Pharmacokinetic–pharmacodynamic integration and modelling of oxytetracycline for the calf pathogens Mannheimia haemolytica and Pasteurella multocida [PDF]
A calf tissue cage model was used to study the pharmacokinetics (PK) and pharmacodynamics (PD) of oxytetracycline in serum, inflamed (exudate) and noninflamed (transudate) tissue cage fluids.
Aliabadi +45 more
core +3 more sources
Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts [PDF]
Beside the major effect of acute thrombus formation, little is known about the interaction of platelets with the coronary endothelium in an ischaemia–reperfusion situation.
Alloatti +35 more
core +1 more source
Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Becker, Bernhard F. +4 more
core +1 more source
Transudative Malignancy: Uncommon and Real
Light's criteria are the cornerstone to differentiate exudates from transudates. The traditional literature states that malignant pleural effusions are rarely transudative; therefore, cytology tends to be low yield and not a cost-effective decision. This case describes an 82-year-old female who developed a transudative pleural effusion despite having ...
Cardenas Ramos, Laura +3 more
openaire +2 more sources
Salivary cytokine panel indicative of non-small cell lung cancer. [PDF]
Objective To develop a combinatorial panel of salivary cytokines that manifests the presence of non-small cell lung cancer (NSCLC) that will eventually improve prognosis by facilitating the early diagnosis and management of this common cancer. Methods We
Koizumi, Tomonobu +2 more
core +3 more sources
Background: Differentiating into transudate or exudate is the first step in the evaluation of effusions. Light′s criteria is the standard but a significant number of transudates may not be differentiated based on these criteria. Acute phase proteins (APP)
Girish K Shanthaveeranna +2 more
doaj +1 more source
Gingivocrevicular transudate for HIV screening [PDF]
Producción Científica The use of saliva as an alternative biological fluid to serum in diagnosis or screening of infectious diseases by antibody detection has been the main subject of several articles in the last few years [1, 2, 3, 4, 5, 6]. Saliva samples can be obtained simply, without specialized personnel, and the process is non-traumatic for the ...
Martínez, Prudencio +3 more
openaire +3 more sources
Comparison of standardised versus non-standardised methods for testing the in vitro potency of oxytetracycline against mannheimia haemolytica and pasteurella multocida [PDF]
The in vitro pharmacodynamics of oxytetracycline was established for six isolates of each of the calf pneumonia pathogens Mannheimia haemolytica and Pasteurella multocida.
Aliabadi +26 more
core +4 more sources
Background Pleural effusion is considered an interesting clinical problem that is commonly faced by physicians and is caused by several diseases. The ability of computed tomography (CT) to differentiate transudate effusion from exudate effusion is still ...
Yousef Ahmed +3 more
doaj +1 more source

