Results 131 to 140 of about 12,559 (226)
Abstract This case report presents a recent case of scuticociliatosis in a whitetip reef shark (Triaenodon obesus), housed at a zoo (Haus des Meeres Aqua Terra Zoo, Vienna, Austria). Clinical signs such as uncoordinated swimming and body tilt were observed prior to death.
Hella Schwegler +5 more
wiley +1 more source
Postnatal interaction of size and shape in the human endocranium and brain structures
Ancestral egg‐laying Sceloporus had dorsoventrally tall female pelvises. Two of three live‐bearing clades evolved larger bodies and flatter, wider pelvises, likely reflecting relaxed allometric limits and selection for crypsis or thermoregulation in terrestrial habitats.
Kuranosuke Takagi, Osamu Kondo
wiley +1 more source
The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep
Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller +3 more
wiley +1 more source
Loss of astrocytic MCT1 does not cause late onset neurodegeneration. As ubiquitous MCT1 deletion causes axonal degeneration, oligodendrocytes and potentially other cells are more prominent drivers of MCT1‐mediated metabolic support of neurons. ABSTRACT We recently reported that the loss of oligodendrocyte metabolic support through the lactate and ...
Thomas Philips +9 more
wiley +1 more source
A Portable ULF scanner (1a) imaged a subject (1b) and phantom (1c) to give T2 (2a) and DW (2b) acquisitions alongside a regularised phantom fieldmap (2c). These were processed to give corrected DTI (3a) and CSD (3b) derivatives and were used for whole‐brain tractography (3c) in a feasible acquisition duration.
James Gholam +13 more
wiley +1 more source
Annexin A2 Causes Motor Incoordination via Muscle–Cerebellum Axis in Sarcopenia
ABSTRACT Background Sarcopenia is a prevalent age‐related disorder characterized by progressive muscle atrophy. Impaired balance is one of its most critical clinical consequences, often leading to falling and even bone fractures. As the cerebellum plays a central role in regulating motor coordination, elucidating the molecular mechanisms underlying ...
Xin Jiao +16 more
wiley +1 more source
ABSTRACT Background The loss of smell (anosmia) has been noted in numerous diseases, including COVID‐19. Inflammatory and microstructural alterations are possible underlying mechanisms of anosmia in COVID‐19. However, no atlas exists to study olfaction and the associated tissue property changes.
Marta Gaviraghi +17 more
wiley +1 more source
Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander +4 more
wiley +1 more source
Our results showed that noninvasive electrical stimulation (NES) alone or in combination with human adipose‐derived stem cells (hADSCs)‐induced dopaminergic neuron (NES‐DN) improved the behavioral deficits and pathological features of the MPTP‐induced PD monkey model.
Chunhui Huang +21 more
wiley +1 more source
Efficient and rapid isolation of native AMPA receptor complexes for cryo‐EM
Abstract Isolating native ion channels for structural characterization is routinely achieved by extraction from membrane fractions of tissue with prolonged mild detergent treatment. AMPA receptors (AMPARs), glutamatergic receptors that mediate fast excitatory transmission and synaptic plasticity, are coassembled with diverse auxiliary subunits and ...
Jumi Park, Eric Gouaux
wiley +1 more source

