Results 51 to 60 of about 1,093,627 (309)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Monochorionic Triplet Pregnancy with an Acardiac Twin: A Poor Prognostic Case
ObgyniaIntroduction: Twin Reversed Arterial Perfusion (TRAP) sequence, or acardiac twin, is a rare complication in monochorionic pregnancies due to abnormal placental anastomoses, leading to reversed perfusion and increased risk of heart failure ...
Arlen Resnawaldi +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
InsectsThe Centers for Diseases Control (CDC) light trap is widely used for malaria vector surveillance, but its acquisition logistics pose challenges in Africa. Evaluating new traps can improve surveillance tools.
Billy L. Amugune +6 more
doaj +1 more source
Luminescence mechanism studies on Mn2+/Eu3+ co-doped Zn2GeO4 long afterglow system
四川大学学报. 自然科学版, 2021 Using the first-principles method based on density functional theory, the luminescence mechanism of Mn2+/ Eu3+ co-doped Zn2GeO4 long afterglow system was studied theoretically.
WU Cheng-Guo +3 more
doaj
Umklapp Collisions and Center-of-Mass Oscillations of a Trapped Fermi Gas [PDF]
Physical Review Letters, 2004 Starting from the the Boltzmann equation, we study the center of mass oscillation of a harmonically trapped normal Fermi gas in the presence of a one-dimensional periodic potential. We show that for values of the the Fermi energy above the first Bloch band the center of mass motion is strongly damped in the collisional regime due to umklapp processes ...
Orso, Giuliano +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Advanced Photonics Research, 2021 Lanthanide ions act as excellent luminescence centers and good charge carrier traps. By selecting proper lanthanide ions, persistent phosphors with the desired luminescent color can be developed.
Jumpei Ueda +4 more
doaj +1 more source