Results 81 to 90 of about 1,093,627 (309)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Texas Panhandle Centers [Agency Newsletter]

, 2019
Monthly newsletter discussing news and events related to the Texas Panhandle Centers Behavioral and Development Health and other information about mental ...
Texas Panhandle Centers Behavioral and Development Health
core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya. [PDF]

, 2006
OBJECTIVE: The objective was to measure the efficacy of the vaccination regimen FFM ME-TRAP in preventing episodes of clinical malaria among children in a malaria endemic area.
Lowe, B, Bejon, P, Hill, Adrian, Gilbert, Sarah, Lang Trudie, Lang, T, Peshu, N, Lowe, Brett, Molyneux, C, Fegan Greg, Hill, AV, Milligan Paul, Hill Adrian V. S, Gilbert, Sarah C, Bejon, Philip, Marsh Kevin, Mwacharo Jedidah, Mwangi, T, Mwangi, Tabitha, Fegan, G, Todryk, S, Molyneux, Catherine, Keating, S, Kai, Oscar, Lang, Trudie, Gilbert, SC, Mwacharo, J, Gikonyo, C, Molyneux Catherine, Kai, O, Gilbert Sarah C, Keating, Sheila, Mwangi Tabitha, Todryk, Stephen, Hill, Adrian VS, Kai Oscar, Greg Fegan, Mwacharo, Jedidah, Peshu, Norbert, Todryk Stephen, Milligan, Paul, Marsh, K, Peshu Norbert, Lowe Brett, Gikonyo, Caroline, Bejon Philip, Fegan, Greg, Milligan, P, Keating Sheila, Marsh, Kevin, Gikonyo Caroline   +50 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

On thermoluminescence mechanism and energy leakage in Lu2O3:Tb,V storage phosphor

Optical Materials: X, 2019
The energy storage properties of Lu2O3:Tb,V sintered materials when exposed to X-rays were investigated for the first time using a number of thermoluminescent techniques. Thermoluminescence was generated exclusively by the Tb3+ ions, which served also as
Justyna Zeler, Paulina Bolek, Dagmara Kulesza, Eugeniusz Zych   +3 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Decoding Trap States in Working 2D Perovskite Multi‐Functional Devices

Advanced Science
Hybrid organic–inorganic perovskites, such as 4‐fluorophenethylammonium lead iodide (F‐PEAI), is an emerging class of layered 2D materials of unique interest for a range of opto‐electronic applications, owing to their exceptional photophysical properties
Ioannis Leontis, Karl Jonas Riisnaes, Hoi Tung Lam, Rosanna Mastria, Luisa De Marco, Annalisa Coriolano, Steven Hepplestone, Monica Felicia Craciun, Saverio Russo   +8 more
doaj   +1 more source