Results 51 to 60 of about 120,170 (204)
Backgrounds. Primary osteoarthritis of the proximal interphalangeal joints (PIPJ) is a common entity. It could be associated with local pain that has no effective treatment. Local subcutaneous periarticular injection of methylprednisolone acetate (MPA) was evaluated in a prospective case‐control study. Methods.
George Habib +4 more
wiley +1 more source
Primary cilia disassembly down regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes [PDF]
SummaryObjectiveHedgehog signalling is mediated by the primary cilium and promotes cartilage degeneration in osteoarthritis. Primary cilia are influenced by pathological stimuli and cilia length and prevalence are increased in osteoarthritic cartilage ...
Knight, M.M. +5 more
core +1 more source
International audienceObjectives: Peritrapezial osteoarthritis (OA) includes scaphotrapezial and trapeziometacarpal OA. In clinical practice, scaphotrapezial OA seems better tolerated than trapeziometacarpal OA, with fewer complaints and better tolerance.
Alban Fouasson-Chailloux +11 more
core +1 more source
Ligaments are key structures for stabilizing joints and for sending proprioceptive information to the brain. Nevertheless, their anatomical characteristics have been understudied in the comparative anatomy of primates. The elbow ligaments show a similar gross anatomy in humans and chimpanzees, but their components have different relative sizes in the ...
Josep Maria Potau +9 more
wiley +1 more source
Smoking and Heberden Nodes: Analysis of Data from the Osteoarthritis Initiative
Purpose. Dental hygienists, dentists, and other workforce providers who depend upon their hands for employment are acutely aware of the need to protect their hands to ensure a successful career. Recent research has suggested that smoking may be protective of hand osteoarthritis.
R. Constance Wiener +2 more
wiley +1 more source
Twenty-four flexor carpi radialis (FCR) tendon interposition arthroplasties of the trapezium for bilateral trapeziometacarpal osteoarthritis were reviewed. Pain was reduced in all cases.
Damen, A, vanderLei, B, Robinson, PH
core +1 more source
Excision of the Trapezium for Osteoarthritis of the Trapeziometacarpal Joint of the Thumb
We assessed the results of 86 trapeziectomies in 83 patients. Simple excision of the trapezium was performed in 54 thumbs. This was combined with shortening of the abductor pollicis longus tendon in 14 thumbs and with soft-tissue interposition and/or ligamentous reconstruction in 17 thumbs.
Hollevoet, Nadine +3 more
openaire +4 more sources
Multi‐Scale Analysis of Regional Pathology in the Human Trapezium During Osteoarthritis Progression
ABSTRACT Trapeziometacarpal (TMC) osteoarthritis (OA) is a prevalent condition that significantly impacts hand function and quality of life. In this study we sought to close gaps in knowledge related to the initiation and progression of TMC OA on the tissue scale by evaluating the morphology and gross appearance, wear patterns, mechanical properties ...
Brendan D. Stoeckl +5 more
wiley +1 more source
Leukocyte‐Reduced Platelet‐Rich Plasma Treatment of Basal Thumb Arthritis: A Pilot Study
A positive effect of intra‐articular platelet‐rich plasma (PRP) injection has been discussed for osteoarthritic joint conditions in the last years. The purpose of this study was to evaluate PRP injection into the trapeziometacarpal (TMC) joint. We report about ten patients with TMC joint osteoarthritis (OA) that were treated with 2 intra‐articular PRP ...
Markus Loibl +7 more
wiley +1 more source
Abstract Hand function is important in every aspect of our lives. Across a wide range of neuromuscular disorders—inherited ataxias, motor neuron diseases, polyneuropathies, and myopathies—people can experience losses in hand strength, tone, movement, dexterity, joint range, and sensation.
Colleen O'Connell +5 more
wiley +1 more source

