Results 171 to 180 of about 4,234 (291)

Estimating area under the curve from graph-derived summary data: a systematic comparison of standard and Monte Carlo approaches. [PDF]

BMC Med Res Methodol
Titensor S, Ebbert J, Corte KD, Corte DD.   +3 more
europepmc   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Noisy Graph Patterns via Ordered Matrices

Computer Graphics Forum, EarlyView.
Abstract The high‐level structure of a graph is a crucial ingredient for the analysis and visualization of relational data. However, discovering the salient graph patterns that form this structure is notoriously difficult for two reasons. (1) Finding important patterns, such as cliques and bicliques, is computationally hard.
J. Wulms, W. Meulemans, B. Speckmann
wiley   +1 more source

Human-inspired sensorimotor controller for dynamic motion adaptation: a study in robotic arms. [PDF]

Front Neurorobot
Marchal M, Furnémont R, Verstraten T, Mostafaoui G.   +3 more
europepmc   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Reversal of Glass Transition Temperature at Buried Interfaces in Thermosetting Epoxy Reveals Competition Between Network Maturity and Solid-Induced Confinement. [PDF]

ACS Macro Lett
Abe T, Tajima H, Yasukochi Y, Tanaka K.
europepmc   +1 more source

Aerobic Exercise Training Increases Circulating sRAGE in Adults With Type 2 Diabetes: Associations With Sheddase Regulation

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective Soluble receptor for advanced glycation end‐products (sRAGE) and soluble Toll‐like receptor 4 (sTLR4) are circulating pattern recognition receptor isoforms implicated in inflammatory regulation in type 2 diabetes mellitus (T2DM). This study examined the effects of supervised aerobic exercise training (AET) on circulating sRAGE, sTLR4,
Ryan K. Perkins, Corey E. Mazo, James Shadiow, Pallavi Varshney, Edwin R. Miranda, Victoria R. Miranda, Maggie Eisenberg, Jane E. Nakamura, Elif A. Oral, Jacob M. Haus   +9 more
wiley   +1 more source

Parallel algorithms for phylogenetic inference under a structured coalescent approximation. [PDF]

Proc Natl Acad Sci U S A
Shao Y, Suchard MA, Rambaut A, Ji X, Lemey P, Vasylyeva TI, Baele G.   +6 more
europepmc   +1 more source

Functional immune profiling reveals CD4+ T cell dysregulation in coeliac disease

Immunology &Cell Biology, EarlyView.
The T cell momentum assay quantifies division, survival and activation decay to reveal intrinsic CD4+ programming defects marked by prolonged activation and impaired feedback control in coeliac disease. This scalable platform provides a functional screen for early T cell dysregulation across autoimmune and immune‐mediated diseases.
Anthony J Farchione, HoChan Cheon, David Vremec, Julika Neumann, Gwenny M Verstappen, Melinda Y Hardy, Mai B Margetts, Lauren J Howson, Lee M Henneken, Maureen Forde, Jason A Tye‐Din, Susanne Heinzel, Philip D Hodgkin, Vanessa L Bryant   +13 more
wiley   +1 more source

Surrogate model for statics of fractional thin bar element and its equivalence with mass-spring metamaterial. [PDF]

Sci Rep
Szajek K, Sumelka W.
europepmc   +1 more source