Results 81 to 90 of about 3,680 (277)

Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer

British Journal of Clinical Pharmacology, EarlyView.
Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog, Niven Mehra, Anouk van Kleef, Diederik M. Somford, Inge M. van Oort, Alex L. T. Imholz, Paul Hamberg, Nielka P. van Erp, Emmy Boerrigter   +8 more
wiley   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source

Automated Tuning of PID Controllers Using a Generalized Discrete PID Structure With Particle Swarm Optimization

IEEE Access
Proportional-Integral-Derivative (PID) controllers remain a widely adopted solution in the field of control systems due to their simplicity, flexibility, and ability to control a wide range of processes. Despite their success in various applications, PID
Abdul Aziz Al Barazi, Ercan Aykut
doaj   +1 more source

INVESTIGATION OF INFLUENCE OF SEPARATOR MAGNETIC SYSTEM CONFIGURATION WITH PERMANENT MAGNETS ON MAGNETIC FIELD DISTRIBUTION IN WORKING AREA

Electrical engineering & Electromechanics, 2017
Purpose. To carry out research the influence of magnetic system configuration (shape and size of the permanent magnets) on magnetic field spatial distribution in working area of new structure design magnetic separator with active front surface by ...
J. Gerlici, I.A. Shvedchikova, I.V. Nikitchenko, J.A. Romanchenko   +3 more
doaj   +1 more source

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

British Journal of Clinical Pharmacology, EarlyView.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart, Emiel Leegwater, Thomas H. Ottens, Emile F. Schippers, Erik B. Wilms, David M. Burger, Cees van Nieuwkoop, Liesbeth B. E. Bosma   +7 more
wiley   +1 more source

Solving a System of Fractional-Order Volterra Integro-Differential Equations Based on the Explicit Finite Difference Approximation via the Trapezoid Method with Error Analysis [PDF]

, 2022
Shazad Shawki Ahmed
openalex   +1 more source

Pharmacokinetics, safety, tolerability and fluorescence imaging of nizaracianine triflutate administered in three divided doses to healthy volunteers

British Journal of Clinical Pharmacology, EarlyView.
Aim Fluorescence‐guided surgery enhances intraoperative visualization of anatomical structures. Nizaracianine is a near‐infrared fluorescent agent that is exclusively renally cleared in animal models. It enables real‐time ureteral imaging and identification, potentially reduces risk of injury and facilitates assessment before surgical closure.
Lisanne K. A. Neijenhuis, Cedric M. W. Pesch, John V. Frangioni, Alexander L. Vahrmeijer, Jacobus Burggraaf, Naomi B. Klarenbeek   +5 more
wiley   +1 more source

A Universal and Actionable Measure of Corporate Sustainability for Strategic Decision Making

Business Strategy and the Environment, EarlyView.
ABSTRACT Managers require a universal, comparable, and decision‐useful measure of corporate sustainability that can reliably inform business strategy, yet such a tool remains absent in the literature and current practice. This paper introduces a comprehensive and operational metric—grounded in Goertz's Basic Framework for developing social science ...
Mariapia Pazienza, Martin de Jong, Dirk Schoenmaker   +2 more
wiley   +1 more source

Ultra‐High‐Efficiency On‐Chip CO2 Conversion by Nanosecond Self‐Pulsing Micro‐Plasma Devices

Carbon Energy, EarlyView.
A micro‐plasma chip with sub‐10‐μm electrode gaps is introduced for efficient CO2‐to‐CO conversion. The device self‐converts a DC power supply into nanosecond pulses, producing field‐emission electrons that vibrationally excite CO2, driving dissociation via the ladder‐climbing mechanism. A scaled‐up chip array achieves 30% single‐pass conversion and 50%
Guangyu Sun, Bartu Karakurt, Hongkeng Zhu, Onder Soydal, Jeremy S. Luterbacher, Elison Matioli   +5 more
wiley   +1 more source

Stability Analysis and Finite Difference Approximations for a Damped Wave Equation with Distributed Delay

Mathematics
This paper presents a fully implicit finite difference scheme for the numerical approximation of a wave equation featuring strong damping and a distributed delay term. The discretization employs second-order accurate approximations in both time and space.
Manal Alotaibi
doaj   +1 more source