Results 181 to 190 of about 172,627 (250)

Adversarial Erasing Enhanced Multiple Instance Learning (siMILe): Discriminative Identification of Oligomeric Protein Structures in Single Molecule Localization Microscopy

open access: yesAdvanced Intelligent Systems, EarlyView.
Hallgrimson et al. introduce a machine learning algorithm, siMILe, that takes features of single‐molecule localization microscopy localization clusters (e.g., size and sphericity) and finds the clusters that are associated with certain cell conditions (such as differential protein expression or drug treatment).
Christian Hallgrimson   +8 more
wiley   +1 more source

Optical Tweezers in Emulsion Research: Principles, Advances, and Prospects. [PDF]

open access: yesLangmuir
Ma Q   +8 more
europepmc   +1 more source

Scalable High‐Force Zipping Electrostatic Actuators

open access: yesAdvanced Intelligent Systems, EarlyView.
An electrostatic actuator architecture is presented that combines high energy density with forces and strokes suited for wearable soft robotics. By folding patterned thin films into a scalable honeycomb of zipping units, performance becomes tunable through series–parallel design, achieving over 40 N and 28 J/kg.
Fabio Caruso   +2 more
wiley   +1 more source

Material‐Based Intelligence: Autonomous Adaptation and Embodied Computation in Physical Substrates

open access: yesAdvanced Intelligent Systems, EarlyView.
This perspective formulates a unifying framework for Material‐Based Intelligence (MBI), defining the physical requirements for materials to achieve embodied action, active memory and embodied information processing through intrinsic nonequilibrium dynamics. The design of intelligent materials often draws parallels with the complex adaptive behaviors of
Vladimir A. Baulin   +4 more
wiley   +1 more source

Azetidinylideneketenimines as a Multimodal Synthetic Platform: Coordination Chemistry and Cycloaddition‐Triggered Transformations

open access: yesAngewandte Chemie, EarlyView.
Cross‐coupling/homologation sequence between a stable three‐membered‐ring carbene and isocyanides enables facile and rapid access to novel methyleneketenimines and the first bis(methyleneketenimine). Reactivity studies gave rise to the first methyleneketenimine‐transition metal complexes, unique multimodal reactivity ranging from CO2, isocyanate ...
Taichi Koike   +3 more
wiley   +2 more sources

Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Clotrimazole‐loaded PLGA microparticles for intravaginal delivery. Abstract Background Intravaginal drug administration is the most promising strategy for treating vaginal infections to protect women's health, such as vulvovaginal candidiasis (VVC). However, conventional vaginal formulations in the clinic face challenges such as drug leakage and low ...
Yanyu Li   +8 more
wiley   +1 more source

Merging Biocatalysis and Chemocatalysis in Flow: State‐of‐the‐Art and Future Directions for Sustainable Synthesis

open access: yesAngewandte Chemie, EarlyView.
This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis   +2 more
wiley   +2 more sources

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