Results 11 to 20 of about 31,121 (206)

A robust reprogramming strategy for generating hepatocyte-like cells usable in pharmaco-toxicological studies

Stem Cell Research & Therapy, 2023
Background High-throughput pharmaco-toxicological testing frequently relies on the use of established liver-derived cell lines, such as HepG2 cells. However, these cells often display limited hepatic phenotype and features of neoplastic transformation ...
Guillem Garcia-Llorens, Teresa Martínez-Sena, Eugenia Pareja, Laia Tolosa, José V. Castell, Roque Bort   +5 more
doaj   +1 more source

Duodeno pancreatectomía cefálica laparoscópica

Cirugía del Uruguay, 2022
El abordaje laparoscópico del páncreas es difícil, debido a la localización retroperitoneal y compleja relación vascular. Adecuada experiencia en Whipple convencional y habilidad laparoscópica son pre-requisitos para realizar una duodeno-pancreatéctomia ...
Alan García Alves, Gisela López, Marcos Marani, Álvaro Alcaraz, Enzo Giordano   +4 more
doaj   +1 more source

Ki67 expression at Kasai portoenterostomy as a prognostic factor in patients with biliary atresia

BJS Open, Volume 4, Issue 5, Page 873-883, October 2020., 2020
No consensus exists for predicting outcomes after Kasai portoenterostomy (KP) using liver histological findings. Ki67 (clone, MIB‐1) expression in liver parenchyma was measured by means of immunohistochemical staining of samples from five living donors and 35 patients with biliary atresia to assess its value in predicting KP outcomes.
D. Yoshii, Y. Inomata, Y. Komohara, K. Shimata, M. Honda, S. Hayashida, Y. Oya, H. Yamamoto, H. Yamamoto, Y. Sugawara, T. Hibi   +10 more
wiley   +1 more source

Simulated model of RAPID concept: highlighting innate inflammation and liver regeneration

BJS Open, Volume 4, Issue 5, Page 893-903, October 2020., 2020
The mechanism of RAPID‐associated liver regeneration and its regulation remains unclear. A RAPID model in rats was developed involving cold ischaemia and reperfusion of the selected future liver remnant, portal vein ligation of the remaining segments during step I, and resection of the deportalized lobes during step II.
J. H. Shi, X. Yan, S. J. Zhang, P. D. Line   +3 more
wiley   +1 more source

Outcomes for high‐risk hepatoblastoma in a resource‐challenged setting

BJS Open, Volume 4, Issue 4, Page 630-636, August 2020., 2020
The outcomes of children with high‐risk hepatoblastoma were assessed in the setting of a resource‐challenged nation, where access to organized chemotherapy and liver transplantation remains limited for the underprivileged. Excellent results were demonstrated.
A. Rammohan, M. Rela, G. V. Kumar, J. X. Scott, N. Shanmugam, M. S. Reddy, P. Ramachandran   +6 more
wiley   +1 more source

Donation after circulatory death liver transplantation: consensus statements from the Spanish Liver Transplantation Society

Transplant International, Volume 33, Issue 8, Page 902-916, August 2020., 2020
Summary Livers from donation after circulatory death (DCD) donors are an increasingly more common source of organs for transplantation. While there are few high‐level studies in the field of DCD liver transplantation, clinical practice has undergone progressive changes during the past decade, in particular due to mounting use of postmortem normothermic
Amelia J. Hessheimer, Mikel Gastaca, Eduardo Miñambres, Jordi Colmenero, Constantino Fondevila, in representation of the SETH Working Group on DCD, Javier Briceño, Mireia Caralt, Gloria de la Rosa, José Luis Fernández Aguilar, Yiliam Fundora, F. Agustín García‐Gil, Ignacio González‐Pinto, Laura Lladó, Rafael López‐Andújar, Diego López Guerra, Manuel López Santamaría, Alejandro Manrique, Luis Miguel Marín Gómez, Enrique Moneva, Javier Nuño, Fernando Pardo, Baltasar Pérez Saborido, Pablo Ramírez, José Ignacio Rivas, Gonzalo P. Rodríguez Laíz, Juan Carlos Rodríguez Sanjuan, Patricia Ruíz, Víctor Sánchez Turrión, Evaristo Varo, Enrique Antonio Velasco   +30 more
wiley   +1 more source

Síndrome del linfocito pasajero por anticuerpos anti-D en trasplante hepático. Reporte de caso

Revista Colombiana de Gastroenterología, 2022
El síndrome del linfocito pasajero (PLS) es una complicación de injerto contra huésped que se presenta en el trasplante de órganos sólidos o en el trasplante de células progenitoras hematopoyéticas. Es una causa importante de hemólisis inmune después del
Antonio José Paredes Fernández, Diego Mauricio Gómez-Ramírez, Kenyi Kuratomi nakamura   +2 more
semanticscholar   +1 more source

Liver transplantation for unresectable colorectal liver metastases in patients and donors with extended criteria (SECA‐II arm D study)

BJS Open, Volume 4, Issue 3, Page 467-477, June 2020., 2020
Patients with extensive liver tumour load and a mainly poorly differentiated N2 primary tumour have short overall survival from the time of liver transplantation. Relapses were mostly unresectable and the patients had short survival from the time of relapse. These patients should not be offered liver transplantation.
T. M. Smedman, P.‐D. Line, M. Hagness, T. Syversveen, H. Grut, S. Dueland   +5 more
wiley   +1 more source

FibroScan compared to liver biopsy for accurately staging recurrent hepatic steatosis and fibrosis after transplantation for MASH. [PDF]

Liver Int
Abstract Background and Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD) recurrence after liver transplantation (LT) seems unavoidable and gradual. We aimed to evaluate the diagnostic accuracy in the post‐LT setting of patients transplanted for metabolic dysfunction‐associated steatohepatitis (MASH) of recurrent hepatic steatosis ...
Martínez-Arenas L, Vinaixa C, Conde I, Lorente S, Díaz-Fontenla F, Marques P, Pérez-Rojas J, Montalvá E, Carvalho-Gomes Â, Berenguer M.   +9 more
europepmc   +2 more sources

MANEJO DE LA FALLA HEPÁTICA FULMINANTE: PROPUESTA DE PROTOCOLO EN CLÍNICA LAS CONDES

Revista Médica Clínica Las Condes, 2019
Resumen: La falla hepática fulminante (FHF) es una patología poco frecuente con una alta mortalidad. Requiere un rápido diagnóstico, manejo etiológico, cuando es posible, y una terapia de soporte adecuada en la Unidad de Cuidados Intensivos en la espera ...
Lorena Castro, Leyla Nazal, Guillermo Silva, Javier Brahm, Roberto Segovia, Mario Ferrario, Erwin Buckel, Mario Uribe, Felipe Puelma, Tomás Regueira, Andrés Reccius, Patricia Fardella, María de los Ángeles Rodríguez, Rodrigo Blamey   +13 more
doaj   +1 more source