Results 51 to 60 of about 71,664 (187)

Impact of Molecular Alterations on Survival in Biliary Tract Cancers: A Retrospective Belgian Cohort Study

International Journal of Cancer, EarlyView.
ABSTRACT Biliary tract cancers (BTCs) are aggressive malignancies associated with a poor prognosis. Although molecular profiling is recommended to guide therapeutic decision‐making, real‐practice data on the prevalence and prognostic significance of genomic alterations in European BTC cohorts remain limited.
Jorine Arnouts, Léon C. van Kempen, Senada Koljenović, Helena Oliveres, Pieterjan Vanclooster, Hans Prenen, Caro De Weerdt, Siddharth Chhajlani, Geert Roeyen, Laure Sorber, Koen De Winne, Jonas Dahnoun, Greetje Vanhoutte, Timon Vandamme, Karen Zwaenepoel   +14 more
wiley   +1 more source

Supplementary Figure 3A-B from Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

, 2010
Supplementary Figure 3A-B from Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast ...
Trung Nguyen (309370), Richard Vandlen (108500), Jay Tibbitts (2157649), Hajime Hiraragi (14983245), Guangmin Li (4245022), Richard H. Scheller (14983248), Elaine Mai (501164), Helga Raab (1593514), Sunil Bhakta (2951277), Jagath R. Junutula (1870864), Kelly M. Flagella (14983233), Debra L. Dugger (14983242), Mark X. Sliwkowski (2948271), Gail D. Lewis Phillips (3076089), Edward Ha (14983239), Kathryn L. Parsons (14983236), Richard A. Graham (14982282), Susan D. Spencer (1564864), Paul Polakis (212576), Reina N. Fuji (4448137)   +19 more
core   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Application of MR Cytometry in Predicting Pathologic Complete Response to Neoadjuvant Chemotherapy in Breast Cancer: A Comparative Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MR cytometry imaging is developed to characterize in vivo microstructures. Its clinical value in predicting pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) for breast cancer remains unknown. Purpose To implement MR cytometry to predict pCR for breast cancer and compare the performance of different ...
Jie Ding, Diwei Shi, Shiyun Sun, Jinlong Zheng, Wentao Yang, Caixia Fu, Dazhi Chen, Junzhong Xu, Hua Guo, Chao You, Yajia Gu   +10 more
wiley   +1 more source

Supplementary Figure 2 from Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

, 2010
Supplementary Figure 2 from Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast ...
Trung Nguyen (309370), Richard Vandlen (108500), Jay Tibbitts (2157649), Hajime Hiraragi (14983245), Guangmin Li (4245022), Richard H. Scheller (14983248), Elaine Mai (501164), Helga Raab (1593514), Sunil Bhakta (2951277), Jagath R. Junutula (1870864), Kelly M. Flagella (14983233), Debra L. Dugger (14983242), Mark X. Sliwkowski (2948271), Gail D. Lewis Phillips (3076089), Edward Ha (14983239), Kathryn L. Parsons (14983236), Richard A. Graham (14982282), Susan D. Spencer (1564864), Paul Polakis (212576), Reina N. Fuji (4448137)   +19 more
core   +1 more source

Risk Factors Influencing Efficacy and Prognosis Evaluation of Neoadjuvant Systemic Therapy in Triple‐Positive Breast Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT To identify the determinants of the response to neoadjuvant systemic therapy (NST) in triple‐positive breast cancer (TPBC), we retrospectively enrolled 520 patients with human epidermal growth factor receptor 2 (HER2)‐positive breast cancer who were treated at The First Affiliated Hospital of Chongqing Medical University between January 2015 ...
Lin‐Rui Miao, Hao Liu, Hai‐Ying Yu, Jian Chen, Ming‐Yu Yang, Ya‐Lan Zhang, Gang Tu, Ling‐Feng Tang   +7 more
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

Supplementary Figure 1 from Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

, 2010
Supplementary Figure 1 from Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast ...
Trung Nguyen (309370), Richard Vandlen (108500), Jay Tibbitts (2157649), Hajime Hiraragi (14983245), Guangmin Li (4245022), Richard H. Scheller (14983248), Elaine Mai (501164), Helga Raab (1593514), Sunil Bhakta (2951277), Jagath R. Junutula (1870864), Kelly M. Flagella (14983233), Debra L. Dugger (14983242), Mark X. Sliwkowski (2948271), Gail D. Lewis Phillips (3076089), Edward Ha (14983239), Kathryn L. Parsons (14983236), Richard A. Graham (14982282), Susan D. Spencer (1564864), Paul Polakis (212576), Reina N. Fuji (4448137)   +19 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Supplementary Figure 3C-D from Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

, 2010
Supplementary Figure 3C-D from Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast ...
Trung Nguyen (309370), Richard Vandlen (108500), Jay Tibbitts (2157649), Hajime Hiraragi (14983245), Guangmin Li (4245022), Richard H. Scheller (14983248), Elaine Mai (501164), Helga Raab (1593514), Sunil Bhakta (2951277), Jagath R. Junutula (1870864), Kelly M. Flagella (14983233), Debra L. Dugger (14983242), Mark X. Sliwkowski (2948271), Gail D. Lewis Phillips (3076089), Edward Ha (14983239), Kathryn L. Parsons (14983236), Richard A. Graham (14982282), Susan D. Spencer (1564864), Paul Polakis (212576), Reina N. Fuji (4448137)   +19 more
core   +1 more source