Results 91 to 100 of about 3,051,315 (389)

A paradigm shift: relationships in trauma-informed mental health services

open access: yesBJ Psych Advances, 2018
SUMMARY Trauma-informed approaches emerged partly in response to research demonstrating that trauma is widespread across society, that it is highly correlated with mental health and that this is a costly public health issue.
A. Sweeney   +4 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Reverse suspension syndrome: First report of a novel mechanism of severe trauma

open access: yesTrauma Case Reports, 2019
About 48,000 workers die at the workplace in India due to occupational accidents of which 38 fatal accidents take place every day in the construction sector.
Awaneesh Katiyar   +4 more
doaj   +1 more source

Collective Trauma and the Social Construction of Meaning

open access: yesFrontiers in Psychology, 2018
Collective trauma is a cataclysmic event that shatters the basic fabric of society. Aside from the horrific loss of life, collective trauma is also a crisis of meaning. The current paper systematically delineates the process that begins with a collective
Gilad Hirschberger
semanticscholar   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Death salience moderates the effect of trauma on religiosity [PDF]

open access: yes, 2019
Objective: Previous research has shown contradictory evidence for the relationship between religiosity and trauma; exposure to traumatic life events has been associated with both increases and decreases in religiosity over time.
Bluemke, Matthias   +3 more
core   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Are trauma research programs in academic and non-academic centers measured by equal standards? A survey of 137 level I trauma centers in the United States

open access: yesPatient Safety in Surgery, 2021
Background American College of Surgeons level I trauma center verification requires an active research program. This study investigated differences in the research programs of academic and non-academic trauma centers.
Robert M. Madayag   +7 more
doaj   +1 more source

From Individual To Social Trauma: Sources Of Everyday Trauma In Italy, The US And UK During The Covid-19 Pandemic

open access: yesJournal of Trauma & Dissociation, 2020
The heterogeneity of COVID-19 experience and response for each individual is irrefutable; nevertheless, similarities can be observed between countries with respect to people’s psychological responses.
M. Masiero   +7 more
semanticscholar   +1 more source

Trauma is danger [PDF]

open access: yesJournal of Translational Medicine, 2011
Abstract Background Trauma is one of the leading causes of death in young adult patients. Many pre-clinical and clinical studies attempt to investigate the immunological pathways involved, however the true mediators remain to be elucidated.
Nancy Porterfield   +8 more
openaire   +5 more sources

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