Results 91 to 100 of about 2,944,728 (379)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

The X-Pulley Technique for Subpectoral Long Head of the Biceps Tenodesis Using All-Suture Anchors

Arthroscopy Techniques, 2019
Subpectoral long head of the biceps tenodesis is gaining popularity as a technique for treating patients with various pathologies of the tendon or its anchor to the superior labrum.
Paolo Consigliere, M.D., Shadi Salamat, Nardeen Kader, M.B.B.S., Mohamed Imam, M.D., F.R.C.S.(Orth&Trauma), Abhilash Gowda, F.R.C.S.(Orth&Trauma), A. Ali Narvani, M.B.B.S.(Hons), B.Sc.(Hons), M.Sc.(Sports Med)(Hons), F.R.C.S.(Orth&Trauma), M.F.S.E.M.(UK)   +5 more
doaj  

Shh Signaling from the Injured Lung Microenvironment Drives BMSCs Differentiation into Alveolar Type II Cells for Acute Lung Injury Treatment in Mice

Stem Cells International
Alveolar type II (AT2) cells are key effector cells for repairing damaged lungs. Direct differentiation into AT2 cells from bone marrow mesenchymal stem cells (BMSCs) is a promising approach to treating acute lung injury (ALI).
Mengyu Wu, Jing Liu, Shu Zhang, Yi Jian, Ling Guo, Huacai Zhang, Junwei Mi, Guoxin Qu, Yaojun Liu, Chu Gao, Qingli Cai, Dalin Wen, Di Liu, Jianhui Sun, Jianxin Jiang, Hong Huang   +15 more
doaj   +1 more source

Adjunctive hemoperfusion with Resin Hemoadsorption (HA) 330 cartridges improves outcomes in patients sustaining multiple Blunt Trauma: a prospective, quasi-experimental study

BMC Surgery, 2023
Background Multi-organ dysfunction syndrome and multi-organ failure are the leading causes of late death in patients sustaining severe blunt trauma. So far, there is no established protocol to mitigate these sequelae.
Roham Borazjani, Salahaddin Mahmudi-Azer, Mohammad Hossein Taghrir, Reza Homaeifar, Gholamreza Dabiri, Shahram Paydar, Hossein Abdolrahimzadeh Fard   +6 more
doaj   +1 more source

Knowledge, attitudes, and behavior concerning dental trauma among parents of children attending primary school [PDF]

, 2016
BACKGROUND: Traumatic dental injuries occur frequently in children and adolescents. The purpose of the present study is to examine the levels of knowledge and behaviors regarding dental trauma among parents of children attending primary schools in the ...
Caggiano, G., DE GIGLIO, O, Montagna, Mt, Napoli, Christian, Quaranta, A, Trerotoli, P, Vaccaro, S   +6 more
core   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Trauma no idoso [PDF]

Revista da Associação Médica Brasileira, 2002
The populational growth of the elderly, associated to a healthier and more active life, make this group of people more exposed to accidents. In some countries, trauma in the elderly is responsible for a high mortality rate, disproportionately higher than in the adults.
SOUZA, JOSÉ ANTONIO GOMES DE, IGLESIAS, ANTONIO CARLOS R.G.   +1 more
openaire   +5 more sources

Bayesian decision trees for predicting survival of patients: a study on the US National Trauma Data Bank [PDF]

, 2013
Trauma and Injury Severity Score (TRISS) models have been developed for predicting the survival probability of injured patients the majority of which obtain up to three injuries in six body regions.
Bailey, Becalick, Bouamra, Boyd, Breiman, Brohi, Buntine, Champion, Champion, Chawda, Chipman, Committee on Trauma, Denison, DiRusso, Domingos, Green, Hilden, Hunter, Jakaite, Jakaite, Janis Jakaitis, Kilgo, Kilgo, Livia Jakaite, Millham, Oakland, Osler, Osler, Robert, Rogers, Schetinin, Schetinin, Schetinin, Schetinin, Steyerberg, Subcommittee on Trauma Registry Programs, American College of Surgeons Committee on Trauma, Vitaly Schetinin, Wojtek Krzanowski   +37 more
core   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Endoscopically assisted implant removal of a symphyseal pelvic plate - A case report

Trauma Case Reports, 2021
Introduction: The approach-related morbidity rate in the care of pelvic fractures is still high. Endoscopic procedures are known to significantly reduce access-related complications.
Stephan Regenbogen, Markus Beck, Michael Lang, Markus A. Küper, Fabian M. Stuby, Alexander Trulson   +5 more
doaj