Results 101 to 110 of about 1,751,193 (294)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

The diagnostic value of early cytokine response in patients after major trauma – preliminary report [PDF]

, 2018
Aneta Binkowska, G Michalak, Sławomir Pilip, Maria Kopacz, Robert Słotwiński   +4 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

The Effect on Trauma Care Secondary to the COVID-19 Pandemic

, 2020
Elliott R. Haut, Ira L. Leeds, David H. Livingston   +2 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

An Early Presentation of Tricuspid Valve Rupture in a Trauma Patient With Congenital Heart Disease

Case Reports in Surgery
Tricuspid valve regurgitation/rupture is a rare complication of trauma, with only around 150 cases reported in the literature, though this prevalence may be underestimated due to subtle clinical manifestations.
Justus Boever, Rishi Batra, Hason Khan, Zachary M. Bauman   +3 more
doaj   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Persistent Hypotony Following Antiglaucoma Surgery: A Case Report

Case Reports in Ophthalmological Medicine
Conclusions: Prompt identification and treatment of persistent hypotony post-antiglaucoma surgery are essential for visual function restoration and complication prevention.
Shuxin Cai, Haibo Li, Shuimiao Chen, Ranqing Lin   +3 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

The composite vastus medialis–patellar complex osseomuscular flap as a salvage procedure after complex trauma of the knee—an anatomical study and clinical application [PDF]

, 2005
Elias Polykandriotis, R. Stangl, Heinz Hennig, Jochen K. Lennerz, W. Frank, Milagros Loos, Raymund E. Horch   +6 more
openalex   +1 more source