Results 21 to 30 of about 858,595 (261)

Autologous mesenchymal stem cells or meniscal cells: what is the best cell source for regenerative meniscus treatment in an early osteoarthritis situation?

Stem Cell Research & Therapy, 2017
Background Treatment of meniscus tears within the avascular region represents a significant challenge, particularly in a situation of early osteoarthritis. Cell-based tissue engineering approaches have shown promising results.
Johannes Zellner, Girish Pattappa, Matthias Koch, Siegmund Lang, Johannes Weber, Christian G. Pfeifer, Michael B. Mueller, Richard Kujat, Michael Nerlich, Peter Angele   +9 more
doaj   +1 more source

Cebpb Regulates Skeletal Stem Cell Osteogenic Differentiation and Fracture Healing via the WNT/β-Catenin Pathway

Stem Cells International, 2022
Fracture is the most common traumatic organ injury, and fracture nonunion is a critical clinical challenge. The research on the mechanisms of skeletal stem cell (SSC) differentiation and fracture healing may help develop new treatment strategies and ...
Jiansong Wang, Chensong Yang, Fanyu Kong, Zhi Zhang, Shengchao Ji, Guixin Sun   +5 more
doaj   +1 more source

miR-3960 from Mesenchymal Stem Cell-Derived Extracellular Vesicles Inactivates SDC1/Wnt/β-Catenin Axis to Relieve Chondrocyte Injury in Osteoarthritis by Targeting PHLDA2

Stem Cells International, 2022
Osteoarthritis (OA) is a serious disease of the articular cartilage characterized by excessive inflammation. Lately, mesenchymal stem cell- (MSC-) derived extracellular vesicles (EVs) have been proposed as a novel strategy for the treatment of OA.
Peng Ye, Zhanhu Mi, Daihao Wei, Pengcheng Gao, Mei Ma, Haibo Yang   +5 more
doaj   +1 more source

Long-term outcome following additional rhBMP-7 application in revision surgery of aseptic humeral, femoral, and tibial shaft nonunion

BMC Musculoskeletal Disorders, 2017
Background Surgical revision concepts for the treatment of aseptic humeral, femoral, and tibial diaphyseal nonunion were evaluated. It was analyzed if the range of time to bone healing was shorter, and if clinical and radiological long-term outcome was ...
Simon Hackl, Christian Hierholzer, Jan Friederichs, Alexander Woltmann, Volker Bühren, Christian von Rüden   +5 more
doaj   +1 more source

Rapid prediction of secondary neurologic decline after traumatic brain injury: a data analytic approach

Scientific Reports, 2023
Secondary neurologic decline (ND) after traumatic brain injury (TBI) is independently associated with outcome, but robust predictors of ND are lacking. In this retrospective analysis of consecutive isolated TBI admissions to the R.
Jamie Podell, Shiming Yang, Serenity Miller, Ryan Felix, Hemantkumar Tripathi, Gunjan Parikh, Catriona Miller, Hegang Chen, Yi-Mei Kuo, Chien Yu Lin, Peter Hu, Neeraj Badjatia   +11 more
doaj   +1 more source

Long-term results after thoracoscopic anterior spondylodesis with or without posterior stabilization of unstable incomplete burst fractures of the thoracolumbar junction: a prospective cohort study

Journal of Orthopaedic Surgery and Research, 2020
Background Minimally invasive, thoracoscopic anterior spondylodesis (MIAS) is an established treatment for burst fractures of the thoracolumbar spine. Good restoration of the local sagittal alignment and good functional results have been reported.
Christof Hoffmann, Ulrich Josef Spiegl, Robert Paetzold, Brian Devitt, Stefan Hauck, Thomas Weiss, Volker Bühren, Oliver Gonschorek   +7 more
doaj   +1 more source

Effectiveness after Designation of a Trauma Center: Experience with Operating a Trauma Team at a Private Hospital [PDF]

Journal of Trauma and Injury, 2019
Purpose The present study aimed to evaluate the influence of how the trauma care system applied on the management of trauma patient within the region. Methods We divided the patients in a pre-trauma system group and a post-trauma system group according ...
Kyoung Hwan Kim, Sung Ho Han, Soon-Ho Chon, Joongsuck Kim, Oh Sang Kwon, Min Koo Lee, Hohyoung Lee   +6 more
doaj   +1 more source

The X-Pulley Technique for Subpectoral Long Head of the Biceps Tenodesis Using All-Suture Anchors

Arthroscopy Techniques, 2019
Subpectoral long head of the biceps tenodesis is gaining popularity as a technique for treating patients with various pathologies of the tendon or its anchor to the superior labrum.
Paolo Consigliere, M.D., Shadi Salamat, Nardeen Kader, M.B.B.S., Mohamed Imam, M.D., F.R.C.S.(Orth&Trauma), Abhilash Gowda, F.R.C.S.(Orth&Trauma), A. Ali Narvani, M.B.B.S.(Hons), B.Sc.(Hons), M.Sc.(Sports Med)(Hons), F.R.C.S.(Orth&Trauma), M.F.S.E.M.(UK)   +5 more
doaj   +1 more source

Primary single suture anchor re-fixation of anterior cruciate ligament proximal avulsion tears leads to good functional mid-term results: a preliminary study in 12 patients

Journal of Orthopaedic Surgery and Research, 2017
Background Current studies demonstrate encouraging short-term results after primary anterior cruciate ligament (ACL) suture anchor repair. However, earlier studies reported deterioration of knee function at 5-year follow-up following good clinical short ...
Christof Hoffmann, Jan Friederichs, Christian von Rüden, Christian Schaller, Volker Bühren, Christoph Moessmer   +5 more
doaj   +1 more source

Determinants of Increased Fibrinogen in COVID-19 Patients With and Without Diabetes and Impaired Fasting Glucose

Clinical and Applied Thrombosis/Hemostasis, 2021
Background: To investigate the factors associated with elevated fibrinogen (Fbg) levels in COVID-19 patients with and without diabetes (DM) and impaired fasting glucose (IFG).
Zhenzhou Wang MD, Zhe Du MD, Xiujuan Zhao MD, Fuzheng Guo MD, Tianbing Wang MD, Fengxue Zhu MD   +5 more
doaj   +1 more source