Results 31 to 40 of about 1,751,193 (294)

A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation

Journal of Materials Science: Materials in Medicine, 2021
The extracellular matrix regulates cell survival, proliferation, and differentiation. In vitro two-dimensional cell experiments are typically performed on a plastic plate or a substrate of a single extracellular matrix constituent such as collagen or ...
Weidong Weng, Filippo Zanetti, David Bovard, Bianca Braun, Sabrina Ehnert, Tatiana Uynuk-Ool, Tina Histing, Julia Hoeng, Andreas K. Nussler, Romina H. Aspera-Werz   +9 more
doaj   +1 more source

Should we change our approach to resuscitating victims of femoral fracture? A clinical experience in a busy trauma hospital in Shiraz, Iran

Chinese Journal of Traumatology, 2021
Purpose: Traumatic hemorrhagic shock is a life-threatening event worldwide. Severe brain trauma accompanying femoral fractures can trigger inflammatory responses in the body and increase pre-inflammatory cytokines such as TNF-α, IL-1.
Shahram Paydar, Ali Taheri Akerdi, Sadra Nikseresht, Hossein Abdolrahimzadeh-Fard, Leila Shayan, Zahra Ghahramani, Shahram Bolandparvaz, Hamid Reza Abbasi   +7 more
doaj   +1 more source

Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms

World Psychiatry, 2018
This paper reviews the research evidence concerning the intergenerational transmission of trauma effects and the possible role of epigenetic mechanisms in this transmission. Two broad categories of epigenetically mediated effects are highlighted.
R. Yehuda, A. Lehrner
semanticscholar   +1 more source

Ischemic postconditioning ameliorates acute kidney injury induced by limb ischemia/reperfusion via transforming TLR4 and NF-κB signaling in rats

Journal of Orthopaedic Surgery and Research, 2021
Background The present study investigated the influence of ischemic postconditioning (I-postC) on the adjustment of renal injury after limb ischemia-reperfusion (I/R) injury, to elucidate the mechanisms of the Toll-like receptor 4 (TLR 4)/NF-κB signaling
Zhongdi Liu, Wei Huang, Yifan Chen, Zhe Du, Fengxue Zhu, Tianbing Wang, Baoguo Jiang   +6 more
doaj   +1 more source

American Association for the Surgery of Trauma/American College of Surgeons-Committee on Trauma Clinical Protocol for inpatient venous thromboembolism prophylaxis after trauma

Journal of Trauma and Acute Care Surgery, 2021
Supplemental digital content is available in the text. ABSTRACT Trauma patients are at increased risk of venous thromboembolism (VTE), which includes both deep vein thrombosis and pulmonary embolism.
Brian K. Yorkgitis, Allison E. Berndtson, A. Cross, Ryan O. Kennedy, Matthew P. Kochuba, Christopher J. Tignanelli, G. Tominaga, D. Jacobs, W. Marx, D. Ashley, Eric J. Ley, L. Napolitano, Todd W. Costantini   +12 more
semanticscholar   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

A descriptive survey on the use of resuscitative endovascular balloon occlusion of the aorta (REBOA) for pelvic fractures at US level I trauma centers

Patient Safety in Surgery, 2019
Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) is not widely adopted for pelvic fracture management. Western Trauma Association recommends REBOA for hemodynamically unstable pelvic fractures, whereas Eastern Association for ...
Stephanie Jarvis, Michael Kelly, Charles Mains, Chad Corrigan, Nimesh Patel, Matthew Carrick, Mark Lieser, Kaysie Banton, David Bar-Or   +8 more
doaj   +1 more source

Are trauma research programs in academic and non-academic centers measured by equal standards? A survey of 137 level I trauma centers in the United States

Patient Safety in Surgery, 2021
Background American College of Surgeons level I trauma center verification requires an active research program. This study investigated differences in the research programs of academic and non-academic trauma centers.
Robert M. Madayag, Erica Sercy, Gina M. Berg, Kaysie L. Banton, Matthew Carrick, Mark Lieser, Allen Tanner, David Bar-Or   +7 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source