Parkland Trauma Index of Mortality (PTIM): Real-time Predictive Model for PolyTrauma Patients [PDF]
arXiv, 2020 Vital signs and laboratory values are routinely used to guide clinical decision-making for polytrauma patients, such as the decision to use damage control techniques versus early definitive fracture fixation. Prior multivariate models have tried to predict mortality risk, but due to several limitations like one-time prediction at the time of admission,
arxiv
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Trauma ICU Prevalence Project: the diversity of surgical critical care. [PDF]
, 2019 Background:Surgical critical care is crucial to the care of trauma and surgical patients. This study was designed to provide a contemporary assessment of patient types, injuries, and conditions in intensive care units (ICU) caring for trauma patients ...
+91 more
core +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
FEBS Open Bio, EarlyView.Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu +6 more
wiley +1 more source
Machine Intelligence for Outcome Predictions of Trauma Patients During Emergency Department Care [PDF]
arXiv, 2020 Trauma mortality results from a multitude of non-linear dependent risk factors including patient demographics, injury characteristics, medical care provided, and characteristics of medical facilities; yet traditional approach attempted to capture these relationships using rigid regression models.
arxiv
Aging and Cancer, EarlyView.Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
Diagnostic, demographic, memory quality, and cognitive variables associated with acute stress disorder in children and adolescents [PDF]
, 2007 To date, no studies have investigated factors associated with acute stress disorder (ASD) in children and adolescents. Relationships between ASD and a number of demographic, trauma, cognitive, and trauma memory variables were therefore investigated in a ...
Dalgleish, Tim +4 more
core +1 more source
A Deterministic Method to Calculate the AIS Trauma Score from a Finite Element Organ Trauma Model (OTM) [PDF]
arXiv, 2019 Traumatic injuries are measured using the Abbreviated Injury Scale (AIS), which is a risk to life scale. New human computer models use stresses and strains to evaluate whether serious or fatal injuries are reached, unfortunately these tensors bear no direct relation to AIS.
arxiv
Knowledge, attitudes, and behavior concerning dental trauma among parents of children attending primary school [PDF]
, 2016 BACKGROUND: Traumatic dental injuries occur frequently in children and adolescents. The purpose of the present study is to examine the levels of knowledge and behaviors regarding dental trauma among parents of children attending primary schools in the ...
Caggiano, G. +6 more
core +1 more source
Mothers who are Refugees: An analysis of trauma, social support, and parenting efficacy. [PDF]
, 2017 The following exploratory correlational study examined the relationships among trauma severity, social support, and parenting self-efficacy in a sample of mothers who are refugees living in Vermont.
Papka, Sophia Valeria
core +1 more source