Results 41 to 50 of about 81,340 (249)

Accuracy of Kampala Trauma Score as a Predictor in Assessing the Prognostic Value of Multiple Trauma

open access: yesMajalah Kedokteran Bandung, 2023
Determining a trauma scoring system appropriate for certain conditions will help in predicting mortality and morbidity, and can determine the need for treatment in patients.
Nurhayat Usman   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Non-operative management of blunt abdominal trauma: positive predictors

open access: yesAlʹmanah Kliničeskoj Mediciny, 2017
Background: Over the last years a non-operative management (NOM) of blunt  abdominal  trauma has been included into the standard treatment guidelines  in leading  trauma  centers  all over the world.
A. A. Pankratov   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Using Scoring Systems to Predict Thoracic Trauma Mortality in Emergency Department Management

open access: yesHamidiye Medical Journal
Background: Thoracic trauma accounts for approximately one-third of trauma cases admitted to the hospital, and approximately 20–25% of trauma-related deaths can be attributed to this type of injury.
Abidin Musa Kapcı   +3 more
doaj   +1 more source

Trauma Scores

open access: yes, 2007
Introduction: For more than 35 years various scoring systems have been used as a method to assess the injury severity of multi-system trauma. They have been used as a tool for triage, for emergency-room quality management, for educational reasons, or nowadays, in order to evaluate the cost-effectiveness of either a complete hospital or a single ...
openaire   +3 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Glasgow Coma Scale Versus Physiologic Scoring Systems in Predicting the Outcome of ICU admitted Trauma Patients; a Diagnostic Accuracy Study

open access: yesArchives of Academic Emergency Medicine, 2022
Introduction: There is no consensus on the performance of decision rules in predicting the prognosis of trauma patients. Therefore, the present study aimed to compare the value of Glasgow coma scale (GCS) and physiologic scoring systems in predicting ...
Sorour Khari   +2 more
doaj   +1 more source

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