Results 51 to 60 of about 17,944,628 (284)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Another step closer to measuring the ghosts in the nursery: preliminary validation of the Trauma Reflective Functioning Scale [PDF]

, 2014
The aim of this study was to examine preliminary evidence of the validity of the Trauma Reflective Functioning Scale and to investigate reflective functioning (RF) and attachment in pregnant women with histories of trauma, with a particular focus on the ...
Berthelot, N, Fonagy, P, Odette eBernazzani, Peter eFonagy, Normandin, L, Nicolas eBerthelot, Karin eEnsink, Nicolas Berthelot, Ensink, K, Peter Fonagy, Lina Normandin, Bernazzani, O, Lina eNormandin, Karin Ensink, Odette Bernazzani   +14 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Application of different trauma scoring systems for evaluation of severity of blast injuries

Di-san junyi daxue xuebao, 2019
Objective To assess the performance of different trauma scoring systems for evaluating the severity of blast injuries. Methods Twenty-eight rabbits were exposed to blast injuries induced by explosion in an open field.
KANG Jianyi, DUAN Zhaoxia, ZHANG Jieyuan, ZHANG Dongdong   +3 more
doaj   +1 more source

The Best Prediction Model for Trauma Outcomes of the Current Korean Population: a Comparative Study of Three Injury Severity Scoring Systems [PDF]

Korean Journal of Critical Care Medicine, 2016
Background: Injury severity scoring systems that quantify and predict trauma outcomes have not been established in Korea. This study was designed to determine the best system for use in the Korean trauma population. Methods: We collected and analyzed the
Kyoungwon Jung, John Cook-Jong Lee, Rae Woong Park, Dukyong Yoon, Sungjae Jung, Younghwan Kim, Jonghwan Moon, Yo Huh, Junsik Kwon   +8 more
doaj   +1 more source

The predictive value of CTSI scoring system in non-operative management of patients with splenic blunt trauma: The experience of a level 1 trauma center

European Journal of Radiology Open, 2023
Background: The spleen is one of the most injured organs following blunt abdominal trauma. The management options can be either operative or non-operative management (NOM) with either conservative management or splenic artery embolization.
Ali Barah, Ayman Elmagdoub, Loai Aker, Yaman M. Alahmad, Zeyad Jaleel, Zahoor Ahmed, Rahil Kaassamali, Ammar Al Hasani, Hassan Al-Thani, Ahmed Omar   +9 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

First step toward a better trauma management: Initial results of the Northern Izmir Trauma Registry System for children

, 2019
BACKGROUND: Trauma is an important health problem in children, and improvement in trauma care on the national level is possible only through the knowledge gathered from trauma registry systems.
Kose, Isil, Turgut, Ali, Yaldiz, Demet, Anil, Ayse Berna, Uz, Ilhan, Akbulut, Gokhan, Sofuoglu, Turhan, Anil, Murat, Oztan, Mustafa Onur, Acar, Kerim   +9 more
core   +1 more source

The pulmonary contusion score: Development of a simple scoring system for blunt lung injury

Surgery in Practice and Science
Background: Pulmonary contusions (PC) are common after blunt chest trauma and can be identified with computed tomography (CT). Complex scoring systems for grading PC exist, however recent scoring systems rely on computer-generated algorithms that are not
Lisa J. Toelle, Allison G. McNickle, Declan Feery, Salman Mohammed, Paul J. Chestovich, Kavita Batra, Douglas R. Fraser   +6 more
doaj   +1 more source